CINP and PRRX1

Data Source:
BioGRID (two hybrid)

		CINP	PRRX1
Description		cyclin dependent kinase 2 interacting protein	paired related homeobox 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding HMG Box Domain Binding
	Biological Process	DNA Replication DNA Repair Cell Cycle Cell Division	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Mesenchymal Cell Proliferation Regulation Of Transcription By RNA Polymerase II Embryonic Limb Morphogenesis Inner Ear Morphogenesis Middle Ear Morphogenesis Positive Regulation Of Smoothened Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Determination Embryonic Cranial Skeleton Morphogenesis Artery Morphogenesis Cartilage Development Roof Of Mouth Development Regulation Of Neuron Projection Regeneration Neuronal Stem Cell Population Maintenance Positive Regulation Of DNA Repair By Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Body mass index ( 26426971) Refractive error ( 32231278)	Atrial fibrillation ( 28416818 28416822 29290336 29892015 22544366) Blood protein levels ( 29875488) Calcific aortic valve stenosis ( 32141789) Central corneal thickness ( 32528159) Early onset atrial fibrillation ( 28460022) Emphysema imaging phenotypes ( 26030696) Estimated glomerular filtration rate ( 31152163) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) Hip circumference adjusted for BMI ( 28552196 25673412) Intraocular pressure ( 29617998) Ischemic stroke (cardioembolic) ( 29531354) Macular thickness ( 30535121) Male-pattern baldness ( 29146897 28196072) PR interval ( 32439900) Prevalent atrial fibrillation ( 28416818) Refractive error ( 32231278) Response to angiotensin II receptor blocker therapy ( 22566498) Systemic lupus erythematosus ( 33536424) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		42 interacting genes: AMOTL2 APP ATRIP BAALC BLZF1 BTBD2 C1orf109 CCDC112 CCDC33 CFAP161 CLUAP1 COG3 FAM161B FBF1 FNDC11 GAS8 GOLGA2 HNRNPD INCA1 KANK2 MAGEA3 MEOX2 MINAR1 MMADHC MZT1 NDUFB7 PATJ PAX6 POU6F2 PRC1 PRRX1 PSMA1 REL SERTAD1 SNRPD2 SP2 SYCE1 TEPSIN TXNRD3 ZBTB42 ZNF19 ZNF620	8 interacting genes: CINP GTF2I MAFF MAFG SAAL1 SOX10 SRF SUOX
Entrez ID		51550	5396
HPRD ID		16715	01337
Ensembl ID		ENSG00000100865	ENSG00000116132
Uniprot IDs		A0A024R6M9 Q9BW66	P54821
PDB IDs
Enriched GO Terms of Interacting Partners?
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