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VCX2 and MACROH2A1
Data Source:
BioGRID
(two hybrid)
VCX2
MACROH2A1
Description
variable charge X-linked 2
macroH2A.1 histone
Image
No pdb structure
GO Annotations
Cellular Component
Cellular_component
Nuclear Chromosome
Chromosome, Telomeric Region
Chromatin
Nucleosome
Condensed Chromosome
Sex Chromatin
Barr Body
Nucleus
Nucleoplasm
Pericentric Heterochromatin
Nucleolus
Extracellular Exosome
Molecular Function
Molecular_function
RDNA Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
DNA Binding
Protein Binding
Double-stranded Methylated DNA Binding
Enzyme Binding
Protein Kinase Binding
Protein Serine/threonine Kinase Inhibitor Activity
Chromatin DNA Binding
Nucleosomal DNA Binding
Protein Heterodimerization Activity
Promoter-specific Chromatin Binding
Biological Process
Brain Development
Biological_process
Negative Regulation Of Transcription By RNA Polymerase II
Nucleosome Assembly
Chromatin Silencing
Dosage Compensation
Regulation Of Lipid Metabolic Process
Negative Regulation Of Histone Phosphorylation
Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion
Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Keratinocyte Differentiation
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Histone H3-K4 Methylation
Negative Regulation Of Histone H3-K27 Methylation
Regulation Of Ribosomal DNA Heterochromatin Assembly
Establishment Of Protein Localization To Chromatin
Negative Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Negative Regulation Of Cell Cycle G2/M Phase Transition
Regulation Of Response To Oxidative Stress
Positive Regulation Of Endodermal Cell Differentiation
Negative Regulation Of Protein Localization To Chromosome, Telomeric Region
Pathways
Drugs
Diseases
GWAS
Interacting Genes
9 interacting genes:
BEND7
DDIT4L
GSC2
MACROH2A1
MEOX2
PAX6
STAC3
THAP1
ZNF526
20 interacting genes:
APP
ATF2
ATXN1L
BARD1
BRCA1
CYSRT1
ERICH2
FAM133A
H2BC15
KRTAP10-8
NKAPD1
PARP1
SPOP
SREK1IP1
SRPK1
TRAF2
TRIM26
TRIM59
VCX2
ZNF622
Entrez ID
51480
9555
HPRD ID
06749
13624
Ensembl ID
ENSG00000177504
ENSG00000113648
Uniprot IDs
Q9H322
O75367
PDB IDs
1U35
1ZR3
1ZR5
2F8N
2FXK
3HQH
3HSV
3IID
3IIF
3IVB
5IIT
5LNC
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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