PDE6G and SLC27A2

Data Source:
BioGRID (pull down)

		PDE6G	SLC27A2
Description		phosphodiesterase 6G	solute carrier family 27 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Photoreceptor Outer Segment Membrane Photoreceptor Disc Membrane	Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Integral Component Of Endoplasmic Reticulum Membrane Specific Granule Membrane Extracellular Exosome
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Spectrin Binding CGMP Binding 3',5'-cyclic-GMP Phosphodiesterase Activity	Long-chain Fatty Acid-CoA Ligase Activity Long-chain Fatty Acid Transporter Activity ATP Binding Fatty Acid Transmembrane Transporter Activity Enzyme Binding Very Long-chain Fatty Acid-CoA Ligase Activity Arachidonate-CoA Ligase Activity Cholate-CoA Ligase Activity Phytanate-CoA Ligase Activity Pristanate-CoA Ligase Activity
	Biological Process	Activation Of MAPK Activity Wnt Signaling Pathway, Calcium Modulating Pathway Visual Perception Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Negative Regulation Of Catalytic Activity Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of G Protein-coupled Receptor Signaling Pathway	Fatty Acid Alpha-oxidation Long-chain Fatty Acid Metabolic Process Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Bile Acid Biosynthetic Process Very Long-chain Fatty Acid Catabolic Process Neutrophil Degranulation Long-chain Fatty Acid Import Into Cell Methyl-branched Fatty Acid Metabolic Process
Pathways		Activation of the phototransduction cascade Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Ca2+ pathway Ca2+ pathway	Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Synthesis of bile acids and bile salts via 24-hydroxycholesterol Alpha-oxidation of phytanate Neutrophil degranulation Peroxisomal protein import Peroxisomal protein import
Drugs		Sildenafil Vardenafil 3-isobutyl-1-methyl-7H-xanthine
Diseases		Retinitis pigmentosa (RP)
GWAS		Blond vs. brown/black hair color ( 30531825) High myopia ( 31816047) Refractive error ( 32231278)	Blood metabolite ratios ( 24816252) Platelet count ( 32888494) Verbal declarative memory ( 25648963)
Interacting Genes		11 interacting genes: BHLHE40 DNM2 FNBP1 GNAO1 GRB2 GRK2 L3MBTL3 MAPK3 PRKAB2 SRC TRIP10	4 interacting genes: ABCD1 PEX5 UBC YWHAQ
Entrez ID		5148	11001
HPRD ID		08914	11935
Ensembl ID		ENSG00000185527	ENSG00000140284
Uniprot IDs		P18545	O14975
PDB IDs		3JWR
Enriched GO Terms of Interacting Partners?
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