ISYNA1 and DUSP14

Data Source:
BioGRID (two hybrid)

		ISYNA1	DUSP14
Description		inositol-3-phosphate synthase 1	dual specificity phosphatase 14
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Inositol-3-phosphate Synthase Activity Protein Binding	RNA Binding Protein Tyrosine Phosphatase Activity Protein Binding MAP Kinase Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Inositol Biosynthetic Process Phospholipid Biosynthetic Process Inositol Phosphate Metabolic Process	Inactivation Of MAPK Activity Peptidyl-tyrosine Dephosphorylation
Pathways		Synthesis of IP2, IP, and Ins in the cytosol
Drugs		2-Deoxy-D-Glucitol 6-(E)-Vinylhomophosphonate 2-Deoxy-Glucitol-6-Phosphate Glycerin
Diseases
GWAS		Alzheimer's disease (late onset) ( 30820047) Blood metabolite levels ( 24816252) Breast cancer ( 23535729) Heel bone mineral density ( 30598549)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Monocyte count ( 27863252) Ovarian cancer ( 23535730) Platelet count ( 32888494 27863252) Plateletcrit ( 27863252) Red blood cell count ( 32888494)
Interacting Genes		4 interacting genes: DUSP14 POT1 PPP2CA TRAF4	17 interacting genes: AATK CBY2 CD28 EPHA1 EPHA2 ERBB2 ERBB3 ERBB4 FGFR2 IGF1R ISYNA1 LMTK2 PRMT5 PTK7 ROR1 ROR2 UCHL5
Entrez ID		51477	11072
HPRD ID		17163	09427
Ensembl ID		ENSG00000105655	ENSG00000276023
Uniprot IDs		A0A140VK73 Q9NPH2	O95147 Q6FI36
PDB IDs			2WGP
Enriched GO Terms of Interacting Partners?
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