EVL and BEGAIN

Data Source:
BioGRID (affinity chromatography technology)

		EVL	BEGAIN
Description		Enah/Vasp-like	brain enriched guanylate kinase associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Focal Adhesion Membrane Lamellipodium	Cytoplasm Membrane Synapse
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding	Protein Binding
	Biological Process	Actin Filament Organization Cell Surface Receptor Signaling Pathway Nervous System Development Axon Guidance Actin Polymerization Or Depolymerization Animal Organ Morphogenesis Negative Regulation Of Epithelial Cell Migration Positive Regulation Of Actin Filament Polymerization Actin Nucleation Protein Homotetramerization Positive Regulation Of Stress Fiber Assembly Negative Regulation Of Ruffle Assembly	Regulation Of Postsynaptic Neurotransmitter Receptor Activity
Pathways		Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors RHO GTPases Activate Formins	Neurexins and neuroligins
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) White matter hyperintensities ( 32358547) White matter hyperintensity burden ( 25663218)	Chronotype ( 30696823) Menarche (age at onset) ( 21102462) Metabolite levels ( 23823483) Refractive error ( 32231278)
Interacting Genes		33 interacting genes: ABI1 ABI3 ABL1 APBB1 APBB1IP CRKL DNMBP ENAH FYB1 FYN HCK HTT LYN PFN2 POT1 PRPF40A RAD51 SEMA6A SH3RF1 SPTA1 SPTAN1 SRC TCERG1 TERF1 TES TRIM9 VASP WAS WASL XIRP1 ZDHHC17 ZNF655 ZYX	47 interacting genes: ABLIM1 APP AQP1 ATPAF2 BAHD1 BMP7 CATSPER1 CDC23 DDX6 DEF6 DLG1 DLG4 DTNB ENKD1 FAM107A FAM161A FAM90A1 GEM GFI1B GMCL1 GUCD1 HDAC4 HGS HID1 KIAA0408 KIFC3 LENG1 MAB21L3 PRPF18 PRR35 QSOX1 RASAL3 RBL1 RIBC2 SAXO1 TRAF4 TRIM27 USP2 ZFP64 ZNF250 ZNF319 ZNF417 ZNF572 ZNF587 ZNF648 ZNF774 ZNF835
Entrez ID		51466	57596
HPRD ID		10942	06459
Ensembl ID		ENSG00000196405	ENSG00000183092
Uniprot IDs		A0A024R6K5 Q9UI08	Q9BUH8
PDB IDs
Enriched GO Terms of Interacting Partners?
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