EVL and ATG2B

Data Source:
BioGRID (enzymatic study)

		EVL	ATG2B
Description		Enah/Vasp-like	autophagy related 2B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Focal Adhesion Membrane Lamellipodium	Phagophore Assembly Site Nucleoplasm Endoplasmic Reticulum Membrane Lipid Droplet Extrinsic Component Of Membrane Phagophore Assembly Site Membrane
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding	Phosphatidylinositol-3-phosphate Binding Lipid Transfer Activity
	Biological Process	Actin Filament Organization Cell Surface Receptor Signaling Pathway Nervous System Development Axon Guidance Actin Polymerization Or Depolymerization Animal Organ Morphogenesis Negative Regulation Of Epithelial Cell Migration Positive Regulation Of Actin Filament Polymerization Actin Nucleation Protein Homotetramerization Positive Regulation Of Stress Fiber Assembly Negative Regulation Of Ruffle Assembly	Autophagosome Assembly Autophagy Of Mitochondrion Piecemeal Microautophagy Of The Nucleus Late Nucleophagy Reticulophagy Intermembrane Lipid Transfer
Pathways		Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors RHO GTPases Activate Formins
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) White matter hyperintensities ( 32358547) White matter hyperintensity burden ( 25663218)	Conotruncal heart defects (inherited effects) ( 28468790)
Interacting Genes		33 interacting genes: ABI1 ABI3 ABL1 APBB1 APBB1IP CRKL DNMBP ENAH FYB1 FYN HCK HTT LYN PFN2 POT1 PRPF40A RAD51 SEMA6A SH3RF1 SPTA1 SPTAN1 SRC TCERG1 TERF1 TES TRIM9 VASP WAS WASL XIRP1 ZDHHC17 ZNF655 ZYX
Entrez ID		51466	55102
HPRD ID		10942	12626
Ensembl ID		ENSG00000196405	ENSG00000066739
Uniprot IDs		A0A024R6K5 Q9UI08	Q96BY7
PDB IDs
Enriched GO Terms of Interacting Partners?
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