ZNF107 and HIPK3

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ZNF107	HIPK3
Description		zinc finger protein 107	homeodomain interacting protein kinase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus	Nucleus Cytoplasm Cytosol Plasma Membrane Nuclear Body PML Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Molecular_function Protein Binding Metal Ion Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Biological_process Positive Regulation Of Transcription By RNA Polymerase II	Protein Phosphorylation Apoptotic Process MRNA Transcription Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Negative Regulation Of Apoptotic Process Negative Regulation Of JUN Kinase Activity
Pathways
Drugs			Fostamatinib
Diseases
GWAS		Metabolite levels ( 23823483)	Anger ( 24489884) Obese vs. thin ( 30677029) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		5 interacting genes: HIPK3 HOOK2 KRTAP10-8 SMAD7 U2AF2	37 interacting genes: AR ARRB2 C1QA CREB1 CREBBP DAXX FADD FAS FLNC GLUL GORASP1 GRB2 HEYL HNRNPA1 HNRNPA2B1 HNRNPH1 LIMD1 LIMK2 LIMS2 MBD1 MTMR4 NR2F2 RGS3 SIAH1 SIAH2 SKIL SNIP1 SRSF1 SRSF5 SUMO1 TGFB1I1 TOX4 TP73 TRA2B UBE2I ZNF107 ZYX
Entrez ID		51427	10114
HPRD ID		18669	05111
Ensembl ID		ENSG00000196247	ENSG00000110422
Uniprot IDs		A0A024R5Y9 A0A087WYK5 A0A0B4J2G0 Q8WVL4 Q9UII5	A8KAE4 Q9H422
PDB IDs
Enriched GO Terms of Interacting Partners?
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