PHF21A and LPXN

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PHF21A	LPXN
Description		PHD finger protein 21A	leupaxin
Image
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleoplasm DNA Repair Complex	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Metal Ion Binding	Transcription Coregulator Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Blood Coagulation	Regulation Of Transcription, DNA-templated Cell Adhesion Negative Regulation Of Cell Adhesion Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Adhesion Mediated By Integrin Substrate Adhesion-dependent Cell Spreading Endothelial Cell Migration Negative Regulation Of B Cell Receptor Signaling Pathway Protein-containing Complex Assembly
Pathways		HDACs deacetylate histones Potential therapeutics for SARS Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Axial length ( 24144296) Height ( 29782485) Menarche (age at onset) ( 21102462 25231870) Refractive error ( 32231278) Triglyceride levels ( 32203549) Urate levels ( 31578528)	Inflammatory bowel disease ( 23128233) Lymphoma ( 23349640) Pulse pressure ( 30578418) Ulcerative colitis ( 28067908)
Interacting Genes		18 interacting genes: BANP EXOSC8 FHL2 FHL3 H3C14 HDAC1 HDAC2 HMG20A HMG20B KDM1A KRT40 L3MBTL3 LPXN NUP62 RCOR1 SP3 TRAF1 ZYX	33 interacting genes: AGXT AQP1 GIT1 HDAC6 HOXA1 HOXC9 IKBKG IMP3 ITGA4 LIMS1 LMO1 LMO3 MAP2K7 MAPK6 NDN NR3C1 PHF21A PLEKHH2 PLEKHN1 PLSCR4 POM121 PTK2 PTK2B PTPN12 RNF214 RUNX1T1 SFI1 TGFB1 TNS2 TXLNB VCL ZNF175 ZNF426
Entrez ID		51317	9404
HPRD ID		10516	05651
Ensembl ID		ENSG00000135365	ENSG00000110031
Uniprot IDs		Q96BD5	B7Z5P7 O60711
PDB IDs		2PUY 2YQL	1X3H 4XEF 4XEK 4XEV
Enriched GO Terms of Interacting Partners?
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