FAM53C and KDM3B

Data Source:
BioGRID (affinity chromatography technology)

		FAM53C	KDM3B
Description		family with sequence similarity 53 member C	lysine demethylase 3B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Histone Deacetylase Complex Chromatin Nucleoplasm
	Molecular Function	Protein Binding	Transcription Coregulator Activity Antioxidant Activity Chromatin DNA Binding Histone Demethylase Activity (H3-K9 Specific) Metal Ion Binding Dioxygenase Activity
	Biological Process	Protein Import Into Nucleus	Regulation Of Transcription By RNA Polymerase II Histone H3-K9 Demethylation Response To Cisplatin Cellular Oxidant Detoxification
Pathways			HDMs demethylate histones
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Response to radiotherapy in prostate cancer (toxicity, urinary frequency) ( 27515689) Schizophrenia ( 25056061 30285260)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) HIV-1 susceptibility ( 25786224) Menarche (age at onset) ( 21102462 25231870) Response to radiotherapy in prostate cancer (toxicity, urinary frequency) ( 27515689) Schizophrenia ( 25056061)
Interacting Genes		5 interacting genes: MEOX2 NCK2 SFN SORBS3 YWHAE	6 interacting genes: CREBBP H3-4 RNF41 SPAG8 UBC ZNF512B
Entrez ID		51307	51780
HPRD ID		10785	11055
Ensembl ID		ENSG00000120709	ENSG00000120733
Uniprot IDs		Q9NYF3	Q7LBC6
PDB IDs			4C8D 5R7X 5RAA 5RAB 5RAC 5RAD 5RAE 5RAF 5RAG 5RAH 5RAI 5RAJ 5RAK 5RAL 5RAM 5RAN 5RAO 5RAP 5RAQ 5RAR 5RAS 5RAU 5RAV 5RAW 5RAX 5RAY 5RAZ 5RB0 5RB1 5RB2 5RB3 5RB4 5RB5 5RB6 5RB7 6RBJ
Enriched GO Terms of Interacting Partners?
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