TIMMDC1 and DRAM1

Data Source:
BioGRID (two hybrid)

		TIMMDC1	DRAM1
Description		translocase of inner mitochondrial membrane domain containing 1	DNA damage regulated autophagy modulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane	Cytoplasm Lysosome Lysosomal Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitochondrial Respiratory Chain Complex I Assembly	Autophagy Apoptotic Process Regulation Of Autophagy
Pathways		Complex I biogenesis
Drugs
Diseases
GWAS		Autoimmune thyroid disease ( 32581359) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 31604244 24076602) Primary biliary cholangitis ( 30643196) Primary biliary cirrhosis ( 22961000) Systemic lupus erythematosus ( 28714469) Systemic sclerosis ( 31672989)	Bone mineral density (total hip) ( 29883787) Brain morphology (MOSTest) ( 32665545) Height ( 28552196) Intracranial aneurysm ( 30823506) Systemic lupus erythematosus ( 23273568)
Interacting Genes		70 interacting genes: AGR3 ANKRD46 APOC2 APOC4 APOL3 APP ARL6IP6 ATP6AP2 BCAP31 C14orf180 C3orf52 C4orf3 C5orf46 CCL4 CDS2 CMTM2 CREB3L1 CYP4F12 DCBLD2 DIABLO DRAM1 EPGN FAM20B FAM210B FATE1 FXYD3 GJB2 GPR151 GPR152 GPX8 HGS HSD17B13 IFNA2 KIR2DL4 LHFPL5 MARCHF5 MFSD14B MFSD5 NDUFB11 NINJ1 PEX5 PIGF PTPN1 PTPRN RNF24 SCAMP5 SCD SERF1A SERF1B SERP2 SLC35E4 SLC35F6 SMO ST6GAL2 STX12 STX6 TMEM144 TMEM14B TMEM176A TMEM199 TMEM203 TMEM239 TMEM31 TMEM54 TMEM65 TMEM86A TVP23B UNC93A YIF1A YIPF1	10 interacting genes: APP C1orf21 CD164L2 CLRN1 CREB3 EVI2B GPR42 LRRC4C MS4A7 TIMMDC1
Entrez ID		51300	55332
HPRD ID		12817	07743
Ensembl ID		ENSG00000113845	ENSG00000136048
Uniprot IDs		C9JU35 Q9NPL8	A0A024RBF9 Q8N682
PDB IDs
Enriched GO Terms of Interacting Partners?
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