NT5C3A and DESI1

Data Source:
BioGRID (two hybrid)

		NT5C3A	DESI1
Description		5'-nucleotidase, cytosolic IIIA	desumoylating isopeptidase 1
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol	Nucleus Cytosol Protein-containing Complex
	Molecular Function	Nucleotide Binding TRNA 2'-phosphotransferase Activity Magnesium Ion Binding Protein Binding 5'-nucleotidase Activity	Protein Binding Identical Protein Binding Importin-alpha Family Protein Binding SUMO-specific Isopeptidase Activity
	Biological Process	Pyrimidine Nucleoside Metabolic Process Nucleotide Metabolic Process Dephosphorylation Pyrimidine Nucleoside Catabolic Process Defense Response To Virus	Protein Export From Nucleus Protein Desumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Modification By Small Protein Removal
Pathways
Drugs
Diseases		Anemia due to disorders of nucleotide metabolism, including: Adenylate kinase (AK) deficiency; Uridine 5-prime monophosphate hydrolase (UMPH1) deficiency
GWAS		Estimated glomerular filtration rate ( 31152163) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252)	General cognitive ability ( 29844566) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)
Interacting Genes		6 interacting genes: DESI1 GNAQ NDUFAB1 UBQLN1 UBQLN2 VANGL1	33 interacting genes: ABI3 AGR3 CCDC158 CDIP1 CDSN CTAG1A CTAG1B CTAG2 DAZAP2 ERP29 EVI2B FGF7 GOLM1 KLRF1 MEOX2 NME3 NT5C3A PRR5 RNF4 RPS27A SHISA4 SHISA5 SMIM21 TAS2R41 UBA52 UBB UBC UBQLN1 UBQLN2 UBQLNL UHRF2 XPO1 ZBTB46
Entrez ID		51251	27351
HPRD ID		05871	18590
Ensembl ID		ENSG00000122643	ENSG00000100418
Uniprot IDs		A0A024RA81 A0A090N7U2 Q9H0P0	Q6ICB0
PDB IDs		2CN1 2JGA 2VKQ	3EBQ
Enriched GO Terms of Interacting Partners?
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