PDZD11 and SMG8

		PDZD11	SMG8
Description		PDZ domain containing 11	SMG8 nonsense mediated mRNA decay factor
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Cell-cell Junction Adherens Junction Basolateral Plasma Membrane Synapse Pore Complex Presynapse	Cellular_component Cytosol
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Biotin Metabolic Process Neurotransmitter Secretion Pantothenate Metabolic Process Antimicrobial Humoral Response Ion Transmembrane Transport Maintenance Of Epithelial Cell Apical/basal Polarity Pore Complex Assembly Transmembrane Transport Protein Localization To Basolateral Plasma Membrane	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Protein Kinase Activity
Pathways		Biotin transport and metabolism Vitamin B5 (pantothenate) metabolism Transport of vitamins, nucleosides, and related molecules Ion influx/efflux at host-pathogen interface Ion transport by P-type ATPases	Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Interacting Genes		5 interacting genes: ATP2B2 ATP7A MAGI2 PLEKHA5 SIGMAR1	1 interacting genes: SMG1
Entrez ID		51248	55181
HPRD ID		06622	08551
Ensembl ID		ENSG00000120509	ENSG00000167447
Uniprot IDs		Q5EBL8	Q8ND04
PDB IDs			6L54 6SYT 6Z3R
Enriched GO Terms of Interacting Partners?
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