ACP6 and GNG7

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ACP6	GNG7
Description		acid phosphatase 6, lysophosphatidic	G protein subunit gamma 7
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Heterotrimeric G-protein Complex Plasma Membrane G-protein Beta/gamma-subunit Complex Extracellular Exosome
	Molecular Function	Acid Phosphatase Activity Phosphatase Activity Lysophosphatidic Acid Phosphatase Activity	Protein Binding G-protein Beta-subunit Binding
	Biological Process	Hematopoietic Progenitor Cell Differentiation Phospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Dephosphorylation Lysobisphosphatidic Acid Metabolic Process	G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway
Pathways		Synthesis of PA	Activation of G protein gated Potassium channels Glucagon signaling in metabolic regulation G-protein activation Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion ADP signalling through P2Y purinoceptor 12 G beta:gamma signalling through PI3Kgamma Prostacyclin signalling through prostacyclin receptor Prostacyclin signalling through prostacyclin receptor Adrenaline,noradrenaline inhibits insulin secretion Adrenaline,noradrenaline inhibits insulin secretion Ca2+ pathway Ca2+ pathway G alpha (q) signalling events G alpha (12/13) signalling events G beta:gamma signalling through PLC beta G alpha (s) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 G alpha (i) signalling events G alpha (z) signalling events Glucagon-type ligand receptors Thromboxane signalling through TP receptor Vasopressin regulates renal water homeostasis via Aquaporins Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding G beta:gamma signalling through BTK G beta:gamma signalling through CDC42 Extra-nuclear estrogen signaling ADORA2B mediated anti-inflammatory cytokines production Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Methotrexate-induced interstitial lung disease in rheumatoid arthritis ( 28500057)	Chronotype ( 30696823) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Neutrophil count ( 32888494) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		3 interacting genes: FAM9B GNG7 SLC35F6	8 interacting genes: ACP6 GNB1 GNB2 GNB3 GNB4 GNB5 GORASP2 MPP3
Entrez ID		51205	2788
HPRD ID		16472	10376
Ensembl ID		ENSG00000162836	ENSG00000176533
Uniprot IDs		Q9NPH0	O60262
PDB IDs		4JOB 4JOC 4JOD
Enriched GO Terms of Interacting Partners?
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