RSL24D1 and LSM8

Data Source:
HPRD (two hybrid)

		RSL24D1	LSM8
Description		ribosomal L24 domain containing 1	LSM8 homolog, U6 small nuclear RNA associated
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytosolic Large Ribosomal Subunit	Nucleus Nucleoplasm U6 SnRNP U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Lsm2-8 Complex
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	RNA Binding Protein Binding U6 SnRNA Binding
	Biological Process	Ribosomal Large Subunit Assembly Translation Assembly Of Large Subunit Precursor Of Preribosome	MRNA Splicing, Via Spliceosome RNA Metabolic Process
Pathways			mRNA Splicing - Major Pathway
Drugs		(S)-3-phenyllactic acid Anisomycin Puromycin
Diseases
GWAS		Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Neutrophil count ( 21507922) Proteinuria in chronic kidney disease ( 26420894)	Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Glaucoma (primary open-angle) ( 29891935) Intraocular pressure ( 29617998) Plasma anti-thyroid peroxidase levels ( 29678681) Positive urgency ( 30718321) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Triglyceride levels ( 30108155)
Interacting Genes		7 interacting genes: CDC23 DNMT3L FAM9B FBXO7 LSM8 MCPH1 PEA15	49 interacting genes: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM5 LSM6 LSM7 MAPK8IP2 MGA MINDY1 MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPTIN10 SEPTIN5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1
Entrez ID		51187	51691
HPRD ID		12665	06288
Ensembl ID		ENSG00000137876	ENSG00000128534
Uniprot IDs		A0A024R5U8 Q9UHA3	A4D0W0 O95777
PDB IDs		6LSS 6LU8	3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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