JPT1 and ARHGAP44

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		JPT1	ARHGAP44
Description		Jupiter microtubule associated homolog 1	Rho GTPase activating protein 44
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Nuclear Membrane	Intracellular Anatomical Structure Cytosol Postsynaptic Density Dendrite Leading Edge Membrane Dendritic Spine Presynaptic Active Zone Recycling Endosome Glutamatergic Synapse
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding Phospholipid Binding
	Biological Process		Exocytosis Signal Transduction Regulation Of Actin Cytoskeleton Organization Regulation Of Rac Protein Signal Transduction Negative Regulation Of Rac Protein Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Filopodium Assembly Regulation Of Dendritic Spine Morphogenesis Modification Of Dendritic Spine Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Regulation Of Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane
Pathways			Rho GTPase cycle
Drugs
Diseases
GWAS			Hip circumference adjusted for BMI ( 28552196) Joint mobility (Beighton score) ( 27182965) Multiple system atrophy (pathologically confirmed) ( 27629089)
Interacting Genes		3 interacting genes: ARHGAP44 OTX2 SFPQ	3 interacting genes: CDC42 JPT1 RAC1
Entrez ID		51155	9912
HPRD ID		13665	13810
Ensembl ID		ENSG00000189159	ENSG00000006740
Uniprot IDs		Q9UK76	E7ERK8 Q17R89 Q69Z00
PDB IDs
Enriched GO Terms of Interacting Partners?
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