TFB1M and TFAM

Data Source:
HPRD (in vitro, in vivo)

		TFB1M	TFAM
Description		transcription factor B1, mitochondrial	transcription factor A, mitochondrial
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GO Annotations	Cellular Component	Mitochondrial Matrix Mitochondrial Nucleoid	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Protein-containing Complex Mitochondrial Nucleoid
	Molecular Function	RRNA (adenine-N6,N6-)-dimethyltransferase Activity DNA Binding RNA Binding Protein Binding Mitochondrial Transcription Factor Activity	Transcription Regulatory Region Sequence-specific DNA Binding Mitochondrial Promoter Sequence-specific DNA Binding Transcription Coactivator Binding Chromatin Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding DNA Binding, Bending Heat Shock Protein Binding Mitochondrial Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	RRNA Modification Transcription Initiation From Mitochondrial Promoter Mitochondrion Organization RRNA Methylation	Mitochondrial Transcription Transcription Initiation From Mitochondrial Promoter Mitochondrion Organization Mitochondrial Respiratory Chain Complex Assembly Positive Regulation Of Transcription, DNA-templated
Pathways		Transcriptional activation of mitochondrial biogenesis rRNA modification in the mitochondrion	Mitochondrial transcription initiation Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases
GWAS		Dimensional psychopathology (Arousal) ( 29496196) Dimensional psychopathology (Negative) ( 29496196) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Metabolite levels ( 23823483) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196)	Blood urea nitrogen levels ( 29403010) Height ( 23456168) Metabolite levels ( 23823483) Midgestational circulating levels of PCBs ( 28235828) Refractive error ( 32231278)
Interacting Genes		2 interacting genes: POLRMT TFAM	10 interacting genes: AGTRAP ARL6IP1 COL8A2 MGST3 PNP STATH TECR TFB1M TFB2M TSPAN1
Entrez ID		51106	7019
HPRD ID		09515	02702
Ensembl ID		ENSG00000029639	ENSG00000108064
Uniprot IDs		E5KTM5 Q8WVM0	E5KSU5 Q00059
PDB IDs		6AAX 6AJK	3FGH 3TMM 3TQ6 4NNU 4NOD 6ERP 6ERQ 6HB4 6HC3
Enriched GO Terms of Interacting Partners?
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