SERPINA5 and RIDA

Data Source:
BioGRID (two hybrid)

		SERPINA5	RIDA
Description		serpin family A member 5	reactive intermediate imine deaminase A homolog
Image
GO Annotations	Cellular Component	Acrosomal Membrane Extracellular Region Extracellular Space External Side Of Plasma Membrane Membrane Platelet Alpha Granule Platelet Dense Tubular Network Protein-containing Complex Protein C Inhibitor-TMPRSS7 Complex Protein C Inhibitor-TMPRSS11E Complex Protein C Inhibitor-PLAT Complex Protein C Inhibitor-PLAU Complex Protein C Inhibitor-thrombin Complex Protein C Inhibitor-KLK3 Complex Protein C Inhibitor-plasma Kallikrein Complex Collagen-containing Extracellular Matrix Extracellular Exosome Protein C Inhibitor-coagulation Factor V Complex Protein C Inhibitor-coagulation Factor Xa Complex Protein C Inhibitor-coagulation Factor XI Complex	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Peroxisome Cytosol Extracellular Exosome
	Molecular Function	Retinoic Acid Binding Protease Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Glycosaminoglycan Binding Heparin Binding Phosphatidylcholine Binding Acrosin Binding	RNA Binding MRNA Binding Protein Binding Endoribonuclease Activity, Producing 3'-phosphomonoesters Deaminase Activity 2-iminobutanoate/2-iminopropanoate Deaminase
	Biological Process	Lipid Transport Spermatogenesis Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Blood Coagulation Negative Regulation Of Endopeptidase Activity Negative Regulation Of Hydrolase Activity Seminal Vesicle Development	MRNA Catabolic Process Negative Regulation Of Translation L-threonine Catabolic Process To Glycine MRNA Destabilization RNA Phosphodiester Bond Hydrolysis, Endonucleolytic Organonitrogen Compound Catabolic Process
Pathways		Intrinsic Pathway of Fibrin Clot Formation Common Pathway of Fibrin Clot Formation	Threonine catabolism
Drugs		Urokinase Drotrecogin alfa Tifuvirtide PPL-100
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Serum albumin level ( 29403010) Serum total protein level ( 29403010)
Interacting Genes		22 interacting genes: ACR CBL COPS6 EPS8 F10 F11 F2 FGA FGB FGG KLK1 KLK2 KLK3 KLKB1 PIAS4 PLAT PLAU PROC RCHY1 RIDA SEMG2 THBD	10 interacting genes: BANP DEAF1 HIVEP1 HPD MDM2 MT-CO2 SERPINA5 SPEN TMEM176A TRIB3
Entrez ID		5104	10247
HPRD ID		03503	03924
Ensembl ID		ENSG00000188488	ENSG00000132541
Uniprot IDs		A0A024R6N9 B4DDH1 P05154	A0A024R9H2 P52758
PDB IDs		1LQ8 1PAI 2HI9 2OL2 2PAI 3DY0	1ONI
Enriched GO Terms of Interacting Partners?
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