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UBXN1 and PLAA
Data Source:
BioGRID
(two hybrid, two hybrid, biochemical)
UBXN1
PLAA
Description
UBX domain protein 1
phospholipase A2 activating protein
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Cytosol
Dendrite
VCP-NPL4-UFD1 AAA ATPase Complex
Neuronal Cell Body
Nucleus
Cytoplasm
Synapse
Extracellular Exosome
Molecular Function
Protein Binding
Polyubiquitin Modification-dependent Protein Binding
Ubiquitin Protein Ligase Binding
K48-linked Polyubiquitin Modification-dependent Protein Binding
Ubiquitin Binding
ATPase Binding
K6-linked Polyubiquitin Modification-dependent Protein Binding
Proteasome Regulatory Particle Binding
Protein Binding
Phospholipase A2 Activator Activity
Ubiquitin Binding
Biological Process
Protein Folding
Viral Process
Negative Regulation Of Protein Ubiquitination
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Protein K48-linked Deubiquitination
Negative Regulation Of ERAD Pathway
Negative Regulation Of Ubiquitin-specific Protease Activity
Phospholipid Metabolic Process
Prostaglandin Metabolic Process
Inflammatory Response
Signal Transduction
Nervous System Development
Ubiquitin Recycling
Macroautophagy
Positive Regulation Of Phospholipase A2 Activity
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Cellular Response To Lipopolysaccharide
Negative Regulation Of Protein K63-linked Ubiquitination
Positive Regulation Of Synaptic Vesicle Recycling
Positive Regulation Of Dendrite Extension
Positive Regulation Of Neuron Migration
Pathways
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Drugs
Diseases
GWAS
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
3-month functional outcome in ischaemic stroke (modified Rankin score) (
30796134
)
Metabolite levels (
23823483
)
Schizophrenia (
20185149
)
Interacting Genes
19 interacting genes:
ACOT7
ACVR1
BARD1
BMPR1B
BRCA1
FAM189A2
HOMER2
PLA2G4A
PLAA
POLR3C
RAD23A
SMAD1
SMURF1
TGFBR1
TRIM39
UBC
UBE2I
UBQLN1
UBQLN2
6 interacting genes:
HDAC6
KPNA4
PLA2G1B
UBC
UBXN1
VCP
Entrez ID
51035
9373
HPRD ID
11266
04850
Ensembl ID
ENSG00000162191
ENSG00000137055
Uniprot IDs
A0A024R539
A0A024R598
A0A087WTZ5
Q04323
Q9Y263
PDB IDs
2K89
2K8A
2K8B
2K8C
3EBB
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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