NTM and LINGO1

Data Source:
BioGRID (two hybrid)

		NTM	LINGO1
Description		neurotrimin	leucine rich repeat and Ig domain containing 1
Image
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Anchored Component Of Membrane	Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Matrix
	Molecular Function	Protein Binding	Epidermal Growth Factor Receptor Binding Protein Binding
	Biological Process	Cell Adhesion Neuron Recognition	Negative Regulation Of Axonogenesis
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Axonal growth inhibition (RHOA activation)
Drugs
Diseases
GWAS		Adult body size ( 32376654) Aggressiveness in attention deficit hyperactivity disorder ( 27021288) Asperger disorder ( 21182207) Blood protein levels ( 30072576) Body size at age 10 ( 32376654) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Familial lung adenocarcinoma ( 29924316) Feeling worry ( 29500382) Food addiction ( 27106561) Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Glucocorticoid-induced osteonecrosis (time dependent analysis) ( 26265699) Gut microbiota (functional units) ( 27694959) Intake of total sugars ( 31005972) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Male fertility ( 22633400) Mental health study participation (completed survey) ( 31263887) Myopia ( 27182965) Obesity-related traits ( 23251661) Plasma anti-thyroglobulin levels ( 29678681) Pre-treatment viral load in HIV-1 infection ( 31219150) Refractive error ( 32231278) Serum polyunsaturated fatty acid concentration x sex interaction in metabolic syndrome ( 31991592) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Sunburns ( 23548203)	Adult body size ( 32376654) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Essential tremor ( 19182806) Feeling miserable ( 29500382) General factor of neuroticism ( 30867560) Hemoglobin A1c levels ( 29403010) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Neuroticism ( 27089181) Risky sexual behaviors (alcohol dependence interaction) ( 28990359) Systemic lupus erythematosus ( 33536424)
Interacting Genes		20 interacting genes: APP C19orf47 CCKBR EFEMP2 KRTAP1-1 KRTAP3-2 KRTAP5-9 KRTAP9-3 LHB LINGO1 LSAMP MRPL12 NBPF19 NEGR1 NOTCH2NLA P4HB PAX4 QRFPR SPRY1 VWC2	17 interacting genes: EFEMP2 FBLN1 FBXW7 FRS3 GOLGA2 HSD3B7 KRTAP10-1 KRTAP4-12 KRTAP5-6 KRTAP5-9 KRTAP9-2 MACO1 NGFR NTM RTN4R SPAG5 TRIM27
Entrez ID		50863	84894
HPRD ID		06398	14322
Ensembl ID		ENSG00000182667	ENSG00000169783
Uniprot IDs		B7Z1I4 Q9P121	Q96FE5
PDB IDs		6DLF	2ID5 4OQT
Enriched GO Terms of Interacting Partners?
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