PAX5 and OSGIN1

Data Source:
BioGRID (two hybrid)

		PAX5	OSGIN1
Description		paired box 5	oxidative stress induced growth inhibitor 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Fibrillar Center Nucleoplasm Cytosol Intracellular Membrane-bounded Organelle	Cellular_component
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding	Protein Binding Growth Factor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Humoral Immune Response Multicellular Organism Development Spermatogenesis Aging Animal Organ Morphogenesis Lateral Ventricle Development Cerebral Cortex Development Adult Behavior Skeletal Muscle Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Cranial Skeleton Morphogenesis Anatomical Structure Development Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of Histone H3-K9 Methylation	Signal Transduction Multicellular Organism Development Cell Differentiation Negative Regulation Of Cell Growth Regulation Of Cell Migration Regulation Of Cell Population Proliferation Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process
Pathways		RUNX1 regulates transcription of genes involved in BCR signaling
Drugs
Diseases		Lymphoplasmacytic lymphoma
GWAS		Adult body size ( 32376654) Alzheimer's disease ( 30636644) Composite immunoglobulin trait (IgA/IgM) ( 28628107) Coronary artery disease in type 1 diabetes ( 29695241) HIV-1 susceptibility ( 25786224) Intelligence ( 22449649) Major depressive disorder ( 27479909) Moderate to vigorous physical activity levels ( 29899525) Morning person ( 30696823) Obesity-related traits ( 22013104)	LDL cholesterol ( 30275531) Pursuit maintenance gain ( 29064472) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		55 interacting genes: ACOT12 BCAS2 C1orf109 CCNC CDK3 CIB3 CKS1B CREBBP CSNK2A1 CXorf38 DAXX DTX2 EBF1 EP300 ETS1 FBLN1 GNG13 GRHL2 HGS HMBOX1 HMGB3 HOXC8 ID2 ID3 KLHL38 KPNA1 KPNA2 KRTAP10-8 KRTAP9-3 LARP4 LDLRAP1 LONRF1 MAPK1 MAPK9 MYB NEIL2 NFYC NGLY1 OSGIN1 PNMA5 RAD52 RB1 RNF144B RUNX1 SAE1 SEC14L4 STAC TBP TLE4 TLK2 UBE2I UBE3A UBXN2B UBXN7 ZMYM5	47 interacting genes: AKT1 ARNT2 ATM BCAR3 BEND7 BTBD2 CAPN3 CCDC33 CENPN CRX DECR2 DNAJA3 FGFR4 GCLM HOMEZ IKBKG IKZF3 INCA1 KATNBL1 KRAS KRT75 LNX1 MEI4 MEIS2 MEOX1 MEOX2 MTERF4 PAX5 PDE4A PDE4C PICK1 POLDIP3 POLR2G PPM1D PTEN REL SAXO1 SMARCB1 SORBS3 TCF12 TCF4 TLE5 TRIM54 XRCC3 ZBTB42 ZC2HC1C ZKSCAN4
Entrez ID		5079	29948
HPRD ID		01334	06412
Ensembl ID		ENSG00000196092	ENSG00000140961
Uniprot IDs		C0KTE5 C0KTF5 E7EQT0 E7ERK2 E7ERW5 E7ES87 Q02548	Q9UJX0
PDB IDs		1K78 1MDM
Enriched GO Terms of Interacting Partners?
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