P2RY6 and KRTAP3-3

Data Source:
BioGRID (two hybrid)

		P2RY6	KRTAP3-3
Description		pyrimidinergic receptor P2Y6	keratin associated protein 3-3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Cytosol Keratin Filament
	Molecular Function	G Protein-coupled ADP Receptor Activity G Protein-coupled Receptor Activity Protein Binding G Protein-coupled UDP Receptor Activity G Protein-coupled UTP Receptor Activity	Structural Molecule Activity Protein Binding
	Biological Process	Phagocytosis G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Inositol Trisphosphate Biosynthetic Process G Protein-coupled Purinergic Nucleotide Receptor Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Purine-containing Compound Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Cellular Response To Pyrimidine Ribonucleotide	Keratinization
Pathways		G alpha (q) signalling events P2Y receptors	Keratinization
Drugs
Diseases
GWAS		Refractive error ( 32231278)
Interacting Genes		15 interacting genes: HOXA1 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP3-3 KRTAP5-9 KRTAP9-2 MCFD2 NBPF19 NOTCH2NLA PLSCR1	78 interacting genes: ALDH3B1 ANAPC11 ARID5A ATG9A BEX2 CELF5 CERCAM CTSZ CYSRT1 DCANP1 DCDC2B DMRT3 DOCK2 ERMAP FADS6 FAM168A FARS2 FOXC2 FOXH1 FOXP3 GNE GPS2 GSTP1 GUCD1 HOXA1 HR HYPK KLHL38 KRT83 KRTAP10-1 KRTAP12-3 KRTAP12-4 KRTAP13-2 KRTAP15-1 KRTAP19-2 KRTAP19-7 KRTAP4-11 KRTAP4-2 KRTAP5-6 KRTAP6-2 KRTAP9-3 KRTAP9-8 LASP1 LCE1F LCE2B LCE3A LCE3C LCE3D LCE3E LCE4A LONRF1 LRRN4 MGAT5B MRPL23 MXD3 NR1D2 NTAQ1 NUFIP2 ODF3B OLIG3 OTX1 P2RY6 PATZ1 PHLDA1 PITX1 PITX2 PLSCR3 PLSCR4 PRKAB2 PVR SHISA6 SMARCC1 SSC4D TNFRSF12A VENTX VGLL3 YPEL3 ZNF503
Entrez ID		5031	85293
HPRD ID		03906	13939
Ensembl ID		ENSG00000171631	ENSG00000212899
Uniprot IDs		A0A024R5I9 Q15077	Q9BYR6
PDB IDs		2B6R
Enriched GO Terms of Interacting Partners?
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