ORM2 and BBS5

Data Source:
BioGRID (affinity chromatography technology)

		ORM2	BBS5
Description		orosomucoid 2	Bardet-Biedl syndrome 5
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Azurophil Granule Lumen Specific Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle	Cytosol Axoneme Centriolar Satellite BBSome Ciliary Basal Body Ciliary Membrane
	Molecular Function		RNA Polymerase II Repressing Transcription Factor Binding Protein Binding Phosphatidylinositol-3-phosphate Binding
	Biological Process	Platelet Degranulation Regulation Of Immune System Process Acute-phase Response Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-1 Production Positive Regulation Of Tumor Necrosis Factor Production Neutrophil Degranulation	Heart Looping Visual Perception Protein Transport Melanosome Transport Motile Cilium Assembly Intracellular Transport Response To Stimulus Cilium Assembly
Pathways		Platelet degranulation Neutrophil degranulation	BBSome-mediated cargo-targeting to cilium
Drugs		Disopyramide Lidocaine Imipramine Chlorpromazine Thalidomide Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases			Bardet-Biedl syndrome (BBS)
GWAS		Blood protein levels ( 29875488)	Iris heterochromicity ( 30895295)
Interacting Genes		3 interacting genes: CYP39A1 PRDX6 STK3	2 interacting genes: CRADD KLC3
Entrez ID		5005	129880
HPRD ID		00725	10353
Ensembl ID		ENSG00000228278	ENSG00000163093
Uniprot IDs		P19652	A0A0S2Z626 Q8N3I7
PDB IDs		3APU 3APV 3APW 3APX	6XTB
Enriched GO Terms of Interacting Partners?
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