SLC22A18AS and RRM1

Data Source:
BioGRID (affinity chromatography technology)

		SLC22A18AS	RRM1
Description		solute carrier family 22 member 18 antisense	ribonucleotide reductase catalytic subunit M1
Image		No pdb structure
GO Annotations	Cellular Component		Nuclear Envelope Cytosol Ribonucleoside-diphosphate Reductase Complex Cell Projection Neuronal Cell Body
	Molecular Function		Ribonucleoside-diphosphate Reductase Activity, Thioredoxin Disulfide As Acceptor Protein Binding ATP Binding Identical Protein Binding Ribonucleoside-diphosphate Reductase Activity Disordered Domain Specific Binding
	Biological Process		Mitotic Cell Cycle Pyrimidine Nucleobase Metabolic Process DNA Replication Male Gonad Development Deoxyribonucleotide Biosynthetic Process Response To Ionizing Radiation Nucleobase-containing Small Molecule Interconversion Cell Proliferation In Forebrain Protein Heterotetramerization Retina Development In Camera-type Eye
Pathways			Interconversion of nucleotide di- and triphosphates
Drugs			Cladribine Gemcitabine Clofarabine Hydroxyurea Fludarabine Imexon Gallium maltolate Tezacitabine
Diseases
GWAS		Autism spectrum disorders (repetitive sensory-motor behaviour) ( 32624584) Gout ( 22179738) Malaria ( 31844061)	Malaria ( 31844061) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)
Interacting Genes		6 interacting genes: DTX2 FRS3 INCA1 MTDH NRF1 TTC19	10 interacting genes: BMI1 CDC42 LRIF1 PPP1CC RNF2 RRM2 RRM2B SUMO2 YWHAG ZNF655
Entrez ID		5003	6240
HPRD ID		09127	01588
Ensembl ID		ENSG00000254827	ENSG00000167325
Uniprot IDs		Q8N1D0	B4DXD1 B4E0I8 E9PL69 P23921
PDB IDs			2WGH 3HNC 3HND 3HNE 3HNF 4X3V 5D1Y 5TUS 6AUI 6L3R 6L7L
Enriched GO Terms of Interacting Partners?
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