WRAP73 and TNFRSF8

Data Source:
HPRD (in vitro)

		WRAP73	TNFRSF8
Description		WD repeat containing, antisense to TP73	TNF receptor superfamily member 8
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Microtubule Organizing Center Ciliary Basal Body Mitotic Spindle MWP Complex	Cytoplasm Plasma Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Transmembrane Signaling Receptor Activity
	Biological Process	Mitotic Sister Chromatid Segregation Cell Projection Organization Mitotic Spindle Assembly Protein Localization To Mitotic Spindle Pole Body Positive Regulation Of Non-motile Cilium Assembly	Signal Transduction Negative Regulation Of Cell Population Proliferation Positive Regulation Of TRAIL Production Positive Regulation Of Tumor Necrosis Factor Production Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Apoptotic Process Cellular Response To Mechanical Stimulus
Pathways			TNFs bind their physiological receptors
Drugs			XmAb 2513 Brentuximab vedotin
Diseases
GWAS			Asthma ( 31959851 32296059) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Mosquito bite size ( 28199695) Neutrophil percentage of granulocytes ( 27863252) Sum eosinophil basophil counts ( 27863252) Tuberculosis ( 29036319)
Interacting Genes			7 interacting genes: ALK TDP2 TNFSF8 TRAF1 TRAF2 TRAF3 TRAF5
Entrez ID		49856	943
HPRD ID		06918	01074
Ensembl ID		ENSG00000116213	ENSG00000120949
Uniprot IDs		A0A384MQZ3 Q9P2S5	A5D8T4 P28908
PDB IDs			1D01
Enriched GO Terms of Interacting Partners?
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