OGDH and SERPINB7

Data Source:
BioGRID (affinity chromatography technology)

		OGDH	SERPINB7
Description		oxoglutarate dehydrogenase	serpin family B member 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Mitochondrial Membrane Oxoglutarate Dehydrogenase Complex	Extracellular Space Cytoplasm
	Molecular Function	Oxoglutarate Dehydrogenase (succinyl-transferring) Activity Protein Binding Thiamine Pyrophosphate Binding Metal Ion Binding	Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Generation Of Precursor Metabolites And Energy Glycolytic Process Tricarboxylic Acid Cycle 2-oxoglutarate Metabolic Process Succinyl-CoA Metabolic Process Lysine Catabolic Process Histone Succinylation	Negative Regulation Of Endopeptidase Activity Positive Regulation Of Transforming Growth Factor Beta1 Production Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of Glomerular Mesangial Cell Proliferation Positive Regulation Of Platelet-derived Growth Factor Production
Pathways		Glyoxylate metabolism and glycine degradation Lysine catabolism Citric acid cycle (TCA cycle)
Drugs		NADH Valproic acid Xanthinol
Diseases		Diseases of the tricarboxylic acid cycle, including: Fumarase (FH) deficiency; Succinate dehydrogenase (SDH) deficiency; Alpha-ketoglutarate dehydrogenase (AKGDH) deficiency
GWAS		Low density lipoprotein cholesterol levels ( 32154731) Lung cancer in never smokers ( 28604730) Systolic blood pressure change trajectories ( 27980656)	Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 31361310 30929738 32296059 31619474) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma onset (childhood vs adult) ( 30929738) Food allergy ( 29051540) Hen's egg allergy ( 29051540) Systolic blood pressure ( 29208002)
Interacting Genes		5 interacting genes: ANXA2 DLD DLST HSD17B10 PLSCR1
Entrez ID		4967	8710
HPRD ID		08938	04524
Ensembl ID		ENSG00000105953	ENSG00000166396
Uniprot IDs		A0A140VJQ5 B4E3E9 E9PCR7 Q02218	A8K3Q8 O75635
PDB IDs		3ERY
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?