OGDH

Description		oxoglutarate dehydrogenase
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GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Mitochondrial Membrane Oxoglutarate Dehydrogenase Complex
	Molecular Function	Oxoglutarate Dehydrogenase (succinyl-transferring) Activity Protein Binding Thiamine Pyrophosphate Binding Metal Ion Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Glycolytic Process Tricarboxylic Acid Cycle 2-oxoglutarate Metabolic Process Succinyl-CoA Metabolic Process Lysine Catabolic Process Histone Succinylation
Pathways		Glyoxylate metabolism and glycine degradation Lysine catabolism Citric acid cycle (TCA cycle)
Drugs		NADH Valproic acid Xanthinol
Diseases		Diseases of the tricarboxylic acid cycle, including: Fumarase (FH) deficiency; Succinate dehydrogenase (SDH) deficiency; Alpha-ketoglutarate dehydrogenase (AKGDH) deficiency
GWAS		Low density lipoprotein cholesterol levels ( 32154731) Lung cancer in never smokers ( 28604730) Systolic blood pressure change trajectories ( 27980656)
Novel Interacting Genes		1 novel interacting genes: SERPINB7
Interacting Genes		5 interacting genes: ANXA2 DLD DLST HSD17B10 PLSCR1
Entrez ID		4967
HPRD ID		08938
Ensembl ID		ENSG00000105953
Uniprot IDs		A0A140VJQ5 B4E3E9 E9PCR7 Q02218
PDB IDs		3ERY
Enriched GO Terms of Interacting Partners?
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