ODF1 and ODF2

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		ODF1	ODF2
Description		outer dense fiber of sperm tails 1	outer dense fiber of sperm tails 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Outer Dense Fiber Nucleus	Spindle Pole Outer Dense Fiber Nucleus Centrosome Centriole Cytosol Microtubule Sperm Flagellum Ciliary Transition Fiber Centriolar Subdistal Appendage
	Molecular Function	Protein Binding Protein Domain Specific Binding	Structural Molecule Activity Protein Binding
	Biological Process	Multicellular Organism Development Spermatogenesis Cell Differentiation	G2/M Transition Of Mitotic Cell Cycle Multicellular Organism Development Spermatid Development Protein Localization Regulation Of G2/M Transition Of Mitotic Cell Cycle Centriole-centriole Cohesion Cilium Organization Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 28165464 26956414 23770605) IgA nephropathy ( 26028593) IgM levels ( 28628107) Type 2 diabetes (age of onset) ( 28060188)	Body mass index ( 26426971)
Interacting Genes		16 interacting genes: BAG4 CDK5R1 HOXA1 KLC1 KRT86 KRTAP12-2 LCE1C MDFI MEOX2 MTUS2 ODF2 P4HB SPAG4 SPAG5 SYCE1L TRIP6	16 interacting genes: APP FBXO25 ING5 LRRK1 MAP3K1 MARK4 MEOX2 ODF1 RAB8A SMURF1 SNW1 SVIL TRAF5 TRIM55 TRIM63 ZDHHC17
Entrez ID		4956	4957
HPRD ID		01687	03601
Ensembl ID		ENSG00000155087	ENSG00000136811
Uniprot IDs		Q14990	A0A024R8A4 A0A024R8A5 B3KSD5 B4DUU0 B4DX03 B4DX85 Q5BJF6
PDB IDs
Enriched GO Terms of Interacting Partners?
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