OAZ2 and SEC11A

Data Source:
BioGRID (affinity chromatography technology)

		OAZ2	SEC11A
Description		ornithine decarboxylase antizyme 2	SEC11 homolog A, signal peptidase complex subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Signal Peptidase Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Ornithine Decarboxylase Inhibitor Activity	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity
	Biological Process	Regulation Of Cellular Amino Acid Metabolic Process Polyamine Metabolic Process Polyamine Biosynthetic Process Negative Regulation Of Catalytic Activity Positive Regulation Of Protein Catabolic Process Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Polyamine Transmembrane Transport	Signal Peptide Processing
Pathways		Regulation of ornithine decarboxylase (ODC)	SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Synthesis, secretion, and deacylation of Ghrelin
Drugs
Diseases
GWAS		Aluminium levels ( 26025379) Neuroticism ( 29255261)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Response to ketamine in bipolar disorder or major depression (antidepressant effects) ( 30552317) Schizophrenia ( 29483656)
Interacting Genes		5 interacting genes: BDKRB1 CDR2 OAZ1 ODC1 SYTL3	5 interacting genes: ADAM33 BCHE CSNK2B NUPR1 SLC35F6
Entrez ID		4947	23478
HPRD ID		11966	07503
Ensembl ID		ENSG00000180304	ENSG00000140612
Uniprot IDs		O95190	A0A024RC78 H0YKT4 P67812
PDB IDs
Enriched GO Terms of Interacting Partners?
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