SEC11A and SLC35F6

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SEC11A	SLC35F6
Description		SEC11 homolog A, signal peptidase complex subunit	solute carrier family 35 member F6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Signal Peptidase Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleoplasm Mitochondrion Lysosomal Membrane Cytosol Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity	Protein Binding Transmembrane Transporter Activity
	Biological Process	Signal Peptide Processing	Positive Regulation Of Cell Population Proliferation Transmembrane Transport Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Pathways		SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Synthesis, secretion, and deacylation of Ghrelin
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Response to ketamine in bipolar disorder or major depression (antidepressant effects) ( 30552317) Schizophrenia ( 29483656)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		5 interacting genes: ADAM33 BCHE CSNK2B NUPR1 SLC35F6	22 interacting genes: ACP5 ACP6 ALDH2 AQP6 CBARP CERS4 FOLR1 GJA8 GPR152 KIAA0087 KIAA0232 MS4A7 NDUFA4L2 NSG2 OAT PSMG2 SEC11A SEPHS1 SERPINH1 TBPL1 TIMMDC1 TMEM14B
Entrez ID		23478	54978
HPRD ID		07503	12808
Ensembl ID		ENSG00000140612	ENSG00000213699
Uniprot IDs		A0A024RC78 H0YKT4 P67812	Q8N357
PDB IDs
Enriched GO Terms of Interacting Partners?
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