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NUCB2 and STAR
Data Source:
BioGRID
(two hybrid)
NUCB2
STAR
Description
nucleobindin 2
steroidogenic acute regulatory protein
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nuclear Envelope
Endoplasmic Reticulum
Endoplasmic Reticulum-Golgi Intermediate Compartment
Golgi Apparatus
Cytosol
Plasma Membrane
Extracellular Exosome
Mitochondrial Intermembrane Space
Cytosol
Mitochondrial Crista
Neuron Projection
Neuronal Cell Body
Molecular Function
G-protein Alpha-subunit Binding
DNA Binding
Guanyl-nucleotide Exchange Factor Activity
Calcium Ion Binding
Protein Binding
Protein Binding
Cholesterol Binding
Cholesterol Transfer Activity
Biological Process
Small GTPase Mediated Signal Transduction
Negative Regulation Of Appetite
Regulation Of Catalytic Activity
Steroid Biosynthetic Process
Bile Acid Biosynthetic Process
C21-steroid Hormone Biosynthetic Process
Estrogen Biosynthetic Process
Brain Development
Response To Nutrient
Cholesterol Metabolic Process
Glucocorticoid Metabolic Process
Male Gonad Development
Response To Herbicide
Response To Ionizing Radiation
Response To Lead Ion
Positive Regulation Of Gene Expression
Response To Activity
Diterpenoid Metabolic Process
Insecticide Metabolic Process
Biphenyl Metabolic Process
Dibenzo-p-dioxin Metabolic Process
Phenol-containing Compound Metabolic Process
Phthalate Metabolic Process
Intracellular Cholesterol Transport
Cellular Response To Insulin Stimulus
Response To Nicotine
Cellular Response To Interferon-alpha
Response To Drug
Response To Hydrogen Peroxide
Circadian Sleep/wake Cycle, REM Sleep
Negative Regulation Of Neuron Apoptotic Process
Response To Estrogen
Response To Leptin
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Ethanol
Regulation Of Neuronal Synaptic Plasticity
Positive Regulation Of Neurogenesis
Regulation Of Steroid Biosynthetic Process
Response To Corticosterone
Response To Fungicide
Testosterone Biosynthetic Process
Positive Regulation Of Bile Acid Biosynthetic Process
Cellular Response To Lipopolysaccharide
Cellular Response To Antibiotic
Cellular Response To Cadmium Ion
Cellular Response To Alkaloid
Cellular Response To CAMP
Cellular Response To Glucose Stimulus
Cellular Response To Interferon-gamma
Cellular Response To Follicle-stimulating Hormone Stimulus
Cellular Response To Luteinizing Hormone Stimulus
Cellular Response To Growth Hormone Stimulus
Cellular Response To Dexamethasone Stimulus
Cellular Response To Transforming Growth Factor Beta Stimulus
Cellular Response To Epinephrine Stimulus
Intermembrane Lipid Transfer
Pathways
Pregnenolone biosynthesis
Drugs
Calcium citrate
Calcium Phosphate
Calcium phosphate dihydrate
Diseases
46,XY disorders of sex development (Disorders in androgen synthesis or action), including: Congenital adrenal hyperplasias; Leydig cell hypoplasia; Androgen insensitivity syndrome (AIS)
Congenital adrenal hyperplasia (CAH)
GWAS
Blood protein levels (
29875488
)
Body mass index (
26426971
)
Height (
20881960
)
Mean platelet volume (
32888494
)
Pulse pressure (
27841878
)
Systolic blood pressure (
27841878
28739976
)
Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) (
28448500
)
Waist circumference adjusted for BMI in active individuals (
28448500
)
Waist circumference adjusted for body mass index (
28448500
)
Youthful appearance (self-reported) (
32339537
)
Menopause (age at onset) (
26414677
)
Orthostatic hypotension (
24124408
)
Schizophrenia (
29483656
)
Interacting Genes
12 interacting genes:
ARL13B
ASPH
FFAR2
GADD45A
GNAI3
GNAS
NDN
NR1I2
SLC7A1
SMARCD1
STAR
XPO1
12 interacting genes:
AGTRAP
CCHCR1
CMTM4
DGAT2L6
FEZ1
LIPE
MAGEA11
MAPK3
NUCB2
RABEP1
SMPD2
STX8
Entrez ID
4925
6770
HPRD ID
09726
02794
Ensembl ID
ENSG00000070081
ENSG00000147465
Uniprot IDs
P80303
Q2L696
P49675
Q6IBK0
PDB IDs
1IMG
2I93
3P0L
5OMA
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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