NNAT and NHLRC1

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		NNAT	NHLRC1
Description		neuronatin	NHL repeat containing E3 ubiquitin protein ligase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Endoplasmic Reticulum Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function		Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Brain Development Protein Lipoylation Positive Regulation Of Insulin Secretion	Protein Polyubiquitination Glycogen Biosynthetic Process Autophagy Regulation Of Gene Expression Positive Regulation Of Protein Ubiquitination Response To Endoplasmic Reticulum Stress Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Kinase Activity Regulation Of Protein Localization To Plasma Membrane
Pathways			Glycogen synthesis Myoclonic epilepsy of Lafora
Drugs
Diseases			Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
GWAS			Intrinsic epigenetic age acceleration ( 29374233)
Interacting Genes		2 interacting genes: APP NHLRC1	9 interacting genes: AGL EPM2A GYS1 NNAT PPP1R3C UBE2D1 UBE2D3 UBE2E1 UBE2H
Entrez ID		4826	378884
HPRD ID		04377	06995
Ensembl ID		ENSG00000053438	ENSG00000187566
Uniprot IDs		A0A3B3ITN5 Q16517	Q6VVB1
PDB IDs
Enriched GO Terms of Interacting Partners?
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