NINJ2 and RIC3

Data Source:
BioGRID (two hybrid)

		NINJ2	RIC3
Description		ninjurin 2	RIC3 acetylcholine receptor chaperone
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane	Golgi Membrane Endoplasmic Reticulum Membrane Integral Component Of Membrane Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle Synapse
	Molecular Function	Protein Binding	Acetylcholine Receptor Binding Protein Folding Chaperone
	Biological Process	Cell Adhesion Neuron Cell-cell Adhesion Nervous System Development Tissue Regeneration	Protein Folding Positive Regulation Of Cytosolic Calcium Ion Concentration Synaptic Transmission, Cholinergic Protein Localization To Cell Surface Cellular Protein-containing Complex Assembly
Pathways
Drugs			Theophylline
Diseases
GWAS		Body mass index ( 26426971) Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte counts ( 32888494 27863252) Mean platelet volume ( 32888494) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Platelet count ( 29403010 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Stroke ( 19369658) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) White blood cell count ( 32888494)	Blood protein levels ( 30072576) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Malaria ( 31844061)
Interacting Genes		74 interacting genes: AMIGO1 AQP6 ARL13B BCL2L13 BTNL9 CD69 CD79A CEACAM3 CHODL CLEC17A CLEC7A CPLX4 CREB3L1 CYBC1 EBP ELOVL4 ELOVL5 EREG ERGIC3 ERVFRD-1 EVI2B FAM209A FAM210B FCGRT FCRL4 FNDC9 GJA1 GPR152 GPR42 ICAM3 IFNGR1 IL3RA JAGN1 KCNJ6 KIR2DL3 KIR3DL3 LDLRAD1 LHFPL5 LMNA LYPD5 LYVE1 M6PR MGST3 MMGT1 MR1 MUC1 ODF4 PIGP PVR RIC3 RNASEK SCN3B SLAMF8 SLC10A1 SLC10A6 SLC66A1 SLC7A14 SLC7A8 STX1A STX2 TM4SF20 TMEM101 TMEM139 TMEM14B TMEM31 TMEM51 TMEM52B TMEM86B TMEM9 TMPRSS2 TMX2 TSPAN12 VMA21 VSIG1	15 interacting genes: BCL2L1 CLN6 FA2H FATE1 GOSR2 NINJ2 PRB1 STX12 STX7 TMBIM1 TMEFF2 TMEM11 TMEM86A TRAF3IP3 YIF1A
Entrez ID		4815	79608
HPRD ID		09530	17974
Ensembl ID		ENSG00000171840	ENSG00000166405
Uniprot IDs		A0A590UJR9 B4DJC1 F5H3L1 F8WBZ3 Q9NZG7	A0A0S2Z607 A0A0S2Z6D3 B7Z3Z0 D3DQU6 Q7Z5B4
PDB IDs
Enriched GO Terms of Interacting Partners?
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