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NFYC and STOX1
Data Source:
BioGRID
(two hybrid)
NFYC
STOX1
Description
nuclear transcription factor Y subunit gamma
storkhead box 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
CCAAT-binding Factor Complex
Protein-DNA Complex
RNA Polymerase II Transcription Regulator Complex
Fibrillar Center
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Protein Heterodimerization Activity
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
Protein Binding
Biological Process
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Protein Folding
Regulation Of Cholesterol Biosynthetic Process
Positive Regulation Of Transcription By RNA Polymerase II
Cell Cycle
Positive Regulation Of Cell Population Proliferation
Regulation Of Gene Expression
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Peptidyl-threonine Phosphorylation
Regulation Of Mitochondrion Organization
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Peptidyl-serine Phosphorylation
Cell Division
Regulation Of Mitochondrial Membrane Potential
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Cellular Response To Nitrosative Stress
Regulation Of Mitochondrial DNA Metabolic Process
Regulation Of Response To Oxidative Stress
Positive Regulation Of Cyclin-dependent Protein Kinase Activity
Pathways
PPARA activates gene expression
Activation of gene expression by SREBF (SREBP)
Activation of gene expression by SREBF (SREBP)
ATF4 activates genes in response to endoplasmic reticulum stress
ATF6 (ATF6-alpha) activates chaperone genes
ATF6 (ATF6-alpha) activates chaperone genes
FOXO-mediated transcription of cell death genes
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Airway obstruction (FEV1/FVC<70%) in never smokers (
30845926
)
Airway obstruction (FEV1/FVC<lower limit of normal) in never smokers (
30845926
)
Depressive and manic episodes in bipolar disorder (
26297903
)
Platelet count (
21507922
)
Refractive error (
32231278
)
Amyotrophic lateral sclerosis (sporadic) (
24529757
)
Interacting Genes
67 interacting genes:
ADGRF5
ADNP2
APOL4
ARID2
ATF6
ATF6B
BDH2
BICRA
BICRAL
CEP76
CIART
CIC
CRX
CSN2
CXorf38
DR1
DST
ELF1
FAM168A
GAPDH
HGS
HIVEP1
HSFY1
HSFY2
KLF11
KLF15
KLHDC7B
LIN54
LMO4
MYC
NFYA
NFYB
NUTM2F
OSTF1
PAX4
PAX5
PAX6
POGZ
POU3F2
POU6F1
POU6F2
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
RAD52
SAE1
SMAD2
SMAD3
SMAP1
SNX2
SP1
SP2
SP4
SREBF2
STOX1
TAF11
TAF12
TAF6
TBP
UBXN7
USF3
ZDHHC17
ZMYM6
ZNF34
ZSCAN1
7 interacting genes:
ADARB1
BANP
GCLM
GORASP2
NFYC
POU2F1
ROR2
Entrez ID
4802
219736
HPRD ID
05633
18579
Ensembl ID
ENSG00000066136
ENSG00000165730
Uniprot IDs
Q13952
Q6ZVD7
PDB IDs
1N1J
4AWL
4CSR
6QMP
6QMQ
6QMS
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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