NFX1 and PPP1R16B

Data Source:
BioGRID (two hybrid)

		NFX1	PPP1R16B
Description		nuclear transcription factor, X-box binding 1	protein phosphatase 1 regulatory subunit 16B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane	Nucleus Plasma Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Protein Phosphatase 1 Binding Myosin Phosphatase Regulator Activity Protein Phosphatase Regulator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Inflammatory Response Viral Process Protein Ubiquitination Negative Regulation Of MHC Class II Biosynthetic Process Protein Autoubiquitination	Positive Regulation Of Endothelial Cell Proliferation Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Protein Dephosphorylation Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Dephosphorylation Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Filopodium Assembly Establishment Of Endothelial Barrier Negative Regulation Of Peptidyl-serine Dephosphorylation Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Sprouting Angiogenesis
Pathways
Drugs
Diseases
GWAS			Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis ( 28714907) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diverticular disease ( 30177863) Huntington's disease progression ( 28642124) Mean corpuscular volume ( 32888494) Platelet distribution width ( 32888494) Schizophrenia ( 25056061 29483656 30285260)
Interacting Genes		9 interacting genes: ELAVL4 MAML3 NUP153 NUP214 NUP62 NUP98 RANBP2 UBC UBE2N	37 interacting genes: ATPAF2 CDCA7L CEP55 CEP70 CRX DVL2 DVL3 FAM83A FARS2 FLYWCH1 GATA1 GFAP GOLGA2 HAPLN2 IKZF3 KCTD9 MAGOH MISP NEFL PATZ1 PHC2 PLEKHN1 PPP1CA PPP1CB RBPMS RFC5 SCNM1 SF3B4 SHC3 TACO1 TADA2A TASOR2 TFIP11 TLE5 TXN2 ZNF410 ZNF564
Entrez ID		4799	26051
HPRD ID		11936	15168
Ensembl ID		ENSG00000086102	ENSG00000101445
Uniprot IDs		Q12986	Q96T49
PDB IDs
Enriched GO Terms of Interacting Partners?
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