SNX20 and SPDEF

Data Source:
BioGRID (two hybrid)

		SNX20	SPDEF
Description		sorting nexin 20	SAM pointed domain containing ETS transcription factor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Early Endosome Membrane	Chromatin Nucleus
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3-phosphate Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Transport	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Negative Regulation Of Cell Fate Commitment Positive Regulation Of Cell Fate Commitment Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Lung Goblet Cell Differentiation Intestinal Epithelial Cell Development
Pathways
Drugs
Diseases
GWAS		Asthma (childhood onset) ( 31036433) Crohn's disease ( 28008999 28067908 22412388) Inflammatory bowel disease ( 28008999 28067908)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 28552196) Inflammatory bowel disease ( 27569725) Refractive error ( 32231278) Weight ( 28552196)
Interacting Genes		8 interacting genes: ALAS1 FAM9B GMCL1 KLHL12 MAGEA11 SPDEF TACC3 TFIP11	12 interacting genes: AR CEP57 COX5A ENKD1 FAM161B NKX3-1 PCGF2 PSMA1 SNX20 SRPK2 STK11 TTC23
Entrez ID		124460	25803
HPRD ID		15401	12176
Ensembl ID		ENSG00000167208	ENSG00000124664
Uniprot IDs		Q7Z614	O95238
PDB IDs			1YO5 2DKX
Enriched GO Terms of Interacting Partners?
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