ATIC and CIP2A

Data Source:
HPRD (in vivo)

		ATIC	CIP2A
Description		5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	cellular inhibitor of PP2A
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GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane Extracellular Exosome	Cytoplasm Cytosol Plasma Membrane Integral Component Of Membrane
	Molecular Function	IMP Cyclohydrolase Activity Phosphoribosylaminoimidazolecarboxamide Formyltransferase Activity Protein Homodimerization Activity Cadherin Binding	Protein Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Brainstem Development Nucleobase-containing Compound Metabolic Process 'de Novo' IMP Biosynthetic Process Nucleoside Metabolic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Response To Inorganic Substance Cerebellum Development Cerebral Cortex Development Animal Organ Regeneration Dihydrofolate Metabolic Process Tetrahydrofolate Biosynthetic Process Cellular Response To Interleukin-7
Pathways		Purine ribonucleoside monophosphate biosynthesis
Drugs		Tetrahydrofolic acid Methotrexate Pemetrexed AICA ribonucleotide Guanosine-5'-Monophosphate 5-monophosphate-9-beta-D-ribofuranosyl xanthine Acid yellow 54 free acid N-[4-([(2-Amino-4-oxo-1,4-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]{(2E)-3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid
Diseases		AICA-ribosiduria; ATIC deficiency
GWAS		Airway imaging phenotypes ( 26030696) Metabolite levels ( 23823483)
Interacting Genes		5 interacting genes: EGFR LINC01554 MTNR1A PRNP SERPINB5	2 interacting genes: MYC STUB1
Entrez ID		471	57650
HPRD ID		03434	11151
Ensembl ID		ENSG00000138363	ENSG00000163507
Uniprot IDs		P31939 V9HWH7	Q8TCG1
PDB IDs		1P4R 1PKX 1PL0 5UY8 5UZ0	5UFL
Enriched GO Terms of Interacting Partners?
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