MYH2 and S100A4

Data Source:
HPRD (in vivo, in vitro)

		MYH2	S100A4
Description		myosin heavy chain 2	S100 calcium binding protein A4
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Muscle Myosin Complex Cell-cell Junction Myofibril Sarcomere Myosin Filament Protein-containing Complex	Extracellular Region Extracellular Space Nucleus Neuron Projection Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Actin Filament Binding	RNA Binding Actin Binding Calcium Ion Binding Protein Binding Identical Protein Binding Transition Metal Ion Binding Calcium-dependent Protein Binding RAGE Receptor Binding
	Biological Process	Muscle Contraction Muscle Filament Sliding Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis	Epithelial To Mesenchymal Transition Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		Regulation of actin dynamics for phagocytic cup formation FCGR3A-mediated phagocytosis
Drugs			Trifluoperazine Copper
Diseases
GWAS			Blood protein levels ( 29875488) Pulse pressure ( 30578418)
Interacting Genes		7 interacting genes: AMPD1 DGKD DUX4L9 OBSCN PRKCE PTK2B S100A4	28 interacting genes: ACTA1 ANXA2 BAG6 CCN3 CEP20 EGFR FCGR3A HSPB1 MDM2 METAP2 MYH10 MYH2 MYH4 MYH9 PPFIBP1 RHOU S100A1 S100B S100P SEPTIN2 SEPTIN6 SEPTIN7 SMAD3 SRPK2 TP53 TPM2 TPM3 UNC119
Entrez ID		4620	6275
HPRD ID		01173	15914
Ensembl ID		ENSG00000125414	ENSG00000196154
Uniprot IDs		Q9UKX2	P26447
PDB IDs			1M31 2LNK 2MRD 2Q91 3C1V 3CGA 3KO0 3M0W 3ZWH 4CFQ 4CFR 4ETO 4HSZ 5LPU 6T58
Enriched GO Terms of Interacting Partners?
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