MYF5 and ITGB4

Data Source:
BioGRID (two hybrid)

		MYF5	ITGB4
Description		myogenic factor 5	integrin subunit beta 4
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm RNA Polymerase II Transcription Regulator Complex	Basement Membrane Nucleolus Plasma Membrane Focal Adhesion Integrin Complex Basal Plasma Membrane Cell Surface Cell Junction Hemidesmosome Cell Leading Edge Nuclear Membrane Receptor Complex Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity E-box Binding	G Protein-coupled Receptor Binding Integrin Binding Protein Binding Insulin-like Growth Factor I Binding Neuregulin Binding
	Biological Process	Cartilage Condensation Ossification Somitogenesis Regulation Of Cell-matrix Adhesion Regulation Of Transcription By RNA Polymerase II Muscle Organ Development Skeletal Muscle Tissue Development Extracellular Matrix Organization Skeletal Muscle Cell Differentiation Muscle Cell Fate Commitment Camera-type Eye Development Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Muscle Cell Differentiation Muscle Tissue Morphogenesis	Autophagy Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Response To Wounding Cell Migration Extracellular Matrix Organization Hemidesmosome Assembly Peripheral Nervous System Myelin Formation Cell Adhesion Mediated By Integrin Nail Development Skin Morphogenesis Filopodium Assembly Mesodermal Cell Differentiation Cell Motility Trophoblast Cell Migration
Pathways		Myogenesis Myogenesis	Assembly of collagen fibrils and other multimeric structures Laminin interactions Syndecan interactions Type I hemidesmosome assembly
Drugs			R1295
Diseases			Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
GWAS
Interacting Genes		34 interacting genes: ANKRD11 AQP1 C14orf119 CALM1 CALM2 CALM3 CCDC13 CHIC2 CSNK2A1 CSNK2A2 ENKD1 FAM124B FIGLA ID1 ID2 ID3 ITGB4 MDFI MSGN1 NHLH2 PACRGL PIN1 RARG SCX SGF29 SNAPC5 TCEANC TCF3 TLE5 ZNF250 ZNF417 ZNF575 ZNF587 ZNF835	59 interacting genes: ADAMTSL4 ALOX12 APPBP2 ATXN1 CLCA1 CLCA2 COL17A1 CYSRT1 DST ECM1 EIF6 ERBB2 ERBIN FYN GRB2 HOXA1 ITGA6 KPRP KRT31 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP15-1 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP4-2 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 MDFI MET MID2 MTUS2 MYF5 NBPF19 NOTCH2NLA PLEC PLSCR4 POU2AF1 PRKCA PRKCD PTK2 SDC2 SDC3 SHC1 SREBF2 TGM1 TRIP6 VIM YES1 YWHAB YWHAQ
Entrez ID		4617	3691
HPRD ID		01168	00946
Ensembl ID		ENSG00000111049	ENSG00000132470
Uniprot IDs		P13349	A0A024R8K7 A0A024R8N2 A0A024R8T0 B7ZLD8 P16144
PDB IDs			1QG3 2YRZ 3F7P 3F7Q 3F7R 3FQ4 3FSO 3H6A 4Q58 4WTW 4WTX 6GVK 6GVL
Enriched GO Terms of Interacting Partners?
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