MX1 and GPC4

Data Source:
HPRD (in vivo, in vitro)

		MX1	GPC4
Description		MX dynamin like GTPase 1	glypican 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Microtubule Cytoskeleton Membrane Axon Cytoplasmic Vesicle Nuclear Membrane Mitochondrial Membrane Dendritic Spine Head Perinuclear Region Of Cytoplasm Presynapse Postsynaptic Endocytic Zone Membrane	Nucleus Golgi Lumen Plasma Membrane External Side Of Plasma Membrane Cell Surface Lysosomal Lumen Synapse Collagen-containing Extracellular Matrix Extracellular Exosome Glutamatergic Synapse Anchored Component Of Presynaptic Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Microtubule Binding Identical Protein Binding	Protein Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway
	Biological Process	Mitochondrial Fission Dynamin Family Protein Polymerization Involved In Mitochondrial Fission Apoptotic Process Defense Response Signal Transduction Response To Virus Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Receptor Internalization Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Regulation Of Synapse Structure Or Activity Defense Response To Virus Type I Interferon Signaling Pathway Membrane Fusion Postsynaptic Neurotransmitter Receptor Internalization	Retinoid Metabolic Process Glycosaminoglycan Biosynthetic Process Glycosaminoglycan Catabolic Process Regulation Of Signal Transduction Wnt Signaling Pathway Cell Migration Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Synaptic Membrane Adhesion Regulation Of Protein Localization To Membrane Regulation Of Presynapse Assembly
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling	A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG biosynthesis HS-GAG degradation Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS Defective B3GALT6 causes EDSP2 and SEMDJL1 Retinoid metabolism and transport
Drugs
Diseases
GWAS
Interacting Genes		41 interacting genes: ACTB ADRM1 APP BLM BRD7 C7orf25 CAB39L CASP8AP2 CBX4 CHD3 DAXX EPM2AIP1 FANCA GMEB1 HMGXB4 KIF26B KLHL35 LRRC4B MCCD1 PIAS1 PIAS2 PLRG1 PSD3 RELA SIAH1 SIRPA SLC25A3 SP100 TDG TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBA1A TUBB ZBTB16 ZCCHC12 ZNF251 ZNF623	10 interacting genes: ABHD17A ACP5 AKAP9 CCNC COL18A1 FGF2 PICK1 PTEN PTPRD PTPRF
Entrez ID		4599	2239
HPRD ID		00919	02160
Ensembl ID		ENSG00000157601	ENSG00000076716
Uniprot IDs		P20591	O75487
PDB IDs		3LJB 3SZR 3ZYS 4P4S 4P4T 4P4U 5GTM
Enriched GO Terms of Interacting Partners?
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