MT-ND5 and GLUL

Data Source:
BioGRID (two hybrid)

		MT-ND5	GLUL
Description		NADH dehydrogenase subunit 5	glutamate-ammonia ligase
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GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Integral Component Of Membrane Neuron Projection	Nucleus Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Plasma Membrane Extracellular Exosome
	Molecular Function	NADH Dehydrogenase Activity NADH Dehydrogenase (ubiquinone) Activity	Glutamate-ammonia Ligase Activity Protein Binding ATP Binding Protein-cysteine S-palmitoyltransferase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Response To Hypoxia Mitochondrial Electron Transport, NADH To Ubiquinone Response To Organonitrogen Compound Electron Transport Coupled Proton Transport Mitochondrial Respiratory Chain Complex I Assembly Response To Hydrogen Peroxide	Neurotransmitter Uptake Angiogenesis Glutamate Catabolic Process Glutamine Biosynthetic Process Cell Population Proliferation Cellular Amino Acid Biosynthetic Process Regulation Of Endothelial Cell Migration Protein Phosphopantetheinylation Protein Palmitoylation Ribosome Biogenesis Regulation Of Sprouting Angiogenesis Regulation Of Protein Localization To Nucleolus
Pathways		Respiratory electron transport Complex I biogenesis	Astrocytic Glutamate-Glutamine Uptake And Metabolism Glutamate and glutamine metabolism
Drugs		NADH	L-Glutamine Glutamic acid
Diseases		Leber optic atrophy; Leber hereditary optic atrophy (LHON)	Congenital systemic glutamine deficiency (CSGD); Glutamine synthetase deficiency
GWAS			Cardiovascular heart disease in diabetics ( 23982368) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) HDL cholesterol levels ( 32203549) Morning person ( 30696823)
Interacting Genes		2 interacting genes: GLUL LIG4	22 interacting genes: CASP8AP2 CRBN CYP39A1 DYNLL1 EP300 HIPK1 HIPK3 HSD17B10 HTR2A MT-ND5 NFKB1 NUDT18 PIAS1 PIAS2 PIAS3 PLEKHF2 PPARD RABEPK RBBP6 SKIL TAT UBE2I
Entrez ID		4540	2752
HPRD ID		02467	00701
Ensembl ID		ENSG00000198786	ENSG00000135821
Uniprot IDs		P03915 U5ZC31	A8YXX4 P15104
PDB IDs		5XTC 5XTD 5XTH 5XTI	2OJW 2QC8
Enriched GO Terms of Interacting Partners?
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