MTIF2 and TSC22D2

Data Source:
BioGRID (two hybrid)

		MTIF2	TSC22D2
Description		mitochondrial translational initiation factor 2	TSC22 domain family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion
	Molecular Function	RNA Binding Translation Initiation Factor Activity GTPase Activity GTP Binding Translation Factor Activity, RNA Binding Ribosomal Small Subunit Binding
	Biological Process	Regulation Of Translational Initiation Ribosome Disassembly Mitochondrial Translational Initiation	Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress
Pathways		Mitochondrial translation initiation
Drugs
Diseases
GWAS		Dementia and core Alzheimer's disease neuropathologic changes ( 25188341)	Adiponectin levels ( 22479202) Apolipoprotein A1 levels ( 32203549) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive decline rate in late mild cognitive impairment ( 26252872) Cortical surface area (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Glaucoma ( 31959993) Glaucoma (primary open-angle) ( 29891935) HDL cholesterol levels ( 32203549) Intraocular pressure ( 29235454) Macular thickness ( 30535121) Mean platelet volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Moyamoya disease ( 29273593) PR interval ( 32439900) Pulse pressure ( 27841878) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 27841878) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149) Triglyceride levels ( 32203549 32154731) Type 2 diabetes ( 30054458 30297969) Waist circumference ( 26785701)
Interacting Genes		3 interacting genes: HSPB1 NFKBIB TSC22D2	42 interacting genes: ANAPC10 ANKRD36 ARID2 ATP1B1 CCDC141 CCDC144A CLIP1 DNAAF11 ENOPH1 EPCAM F8 FLNB GPBP1 ITGA2 KIAA0586 LOXHD1 LPL MED13 MPDZ MSH3 MTIF2 NGRN OSBPL1A PRMT3 PSMA7 PSMA8 RBL1 REV1 RNF2 SAP18 SCEL SEC31A SNX3 SPEF2 STK39 TMA7 TTN UFM1 WNK3 ZMYM2 ZNF143 ZNF251
Entrez ID		4528	9819
HPRD ID		04792	11101
Ensembl ID		ENSG00000085760	ENSG00000196428
Uniprot IDs		P46199 Q6P1N2	B4DN36 O75157
PDB IDs		6GAW 6GAZ 6GB2 6RW5
Enriched GO Terms of Interacting Partners?
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