KRTAP5-6 and RGS19

Data Source:
BioGRID (two hybrid)

		KRTAP5-6	RGS19
Description		keratin associated protein 5-6	regulator of G protein signaling 19
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Golgi Apparatus Plasma Membrane Brush Border Membrane Clathrin-coated Vesicle Membrane Raft
	Molecular Function	Protein Binding	G-protein Alpha-subunit Binding GTPase Activity Protein Binding
	Biological Process	Keratinization	Autophagy G Protein-coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Negative Regulation Of Signal Transduction Response To Ethanol
Pathways		Keratinization	G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events
Drugs
Diseases
GWAS		Logical memory (delayed recall) in mild cognitive impairment ( 29274321)	Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Chronic kidney disease ( 31152163) Coronary artery disease ( 33020668) Estimated glomerular filtration rate ( 31152163) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Systolic blood pressure ( 30578418)
Interacting Genes		79 interacting genes: ADAM12 ADAMTSL4 CATSPER1 CCN3 COL8A1 CRCT1 CREB5 CYSRT1 DDIT4L GLRX3 GUCD1 HOXA1 INCA1 KRT31 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-3 KRTAP13-3 KRTAP17-1 KRTAP26-1 KRTAP3-3 KRTAP4-1 KRTAP4-12 KRTAP4-2 KRTAP5-1 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LBX1 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LINGO1 MAPKBP1 MEOX2 MYPOP NBPF19 NLK NOTCH2NLA NOTO NR1D2 NR4A3 NUFIP2 OTX1 OXER1 PLSCR1 POU4F2 RGS17 RGS19 RGS20 SMCP SPRY2 VGLL3 YY1	25 interacting genes: ALPP CATSPER1 CSNK2A1 CSNK2A2 GDE1 GIPC1 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 KRTAP5-6 LCE4A MAPK1 MAPK6 NUFIP2 OPRL1 OSTM1 OTX1 POU4F2 PRKCA PSMA1 TGFBR1 VASN
Entrez ID		440023	10287
HPRD ID		17250	05461
Ensembl ID		ENSG00000205864	ENSG00000171700
Uniprot IDs		Q6L8G9	B4DP94 P49795
PDB IDs			1CMZ
Enriched GO Terms of Interacting Partners?
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