ASGR2 and SLC35B2

Data Source:
BioGRID (two hybrid)

		ASGR2	SLC35B2
Description		asialoglycoprotein receptor 2	solute carrier family 35 member B2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Endoplasmic Reticulum Quality Control Compartment Perinuclear Region Of Cytoplasm	Golgi Membrane Golgi Apparatus Membrane Integral Component Of Membrane Integral Component Of Golgi Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding	Protein Binding Transmembrane Transporter Activity 3'-phosphoadenosine 5'-phosphosulfate Transmembrane Transporter Activity
	Biological Process	Endocytosis Cell Surface Receptor Signaling Pathway Viral Process Protein N-linked Glycosylation Via Asparagine Bone Mineralization Regulation Of Protein Stability Lipid Homeostasis	Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling 3'-phosphoadenosine 5'-phosphosulfate Transport 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process 3'-phospho-5'-adenylyl Sulfate Transmembrane Transport
Pathways		Asparagine N-linked glycosylation	Transport and synthesis of PAPS Transport of nucleotide sugars
Drugs		Antihemophilic factor, human recombinant Lonoctocog alfa Moroctocog alfa
Diseases
GWAS		Blood protein levels ( 29875488) Congenital heart disease (maternal effect) ( 28468790) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Total cholesterol levels ( 30275531)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		49 interacting genes: ADAM33 ADIPOQ AIG1 ASGR1 ATP6V0C BET1 CD53 CERS2 CLEC17A CLEC7A EMP1 F8 FA2H FATE1 GLP1R GLUD1 HES1 HMOX2 IL1RL1 LAT LNPEP MCEMP1 MMD2 MROH5 MS4A13 NRG1 ORMDL1 PLN PLP2 PMP22 RPRM SEC22A SLC35A1 SLC35B2 SMIM3 STX8 TFRC TMEM140 TMEM60 TMEM86B TMPPE TRAM1L1 TSPO2 UBIAD1 UPK2 VAMP5 VKORC1 VTI1B YIPF1	14 interacting genes: AQP6 ASGR2 CD69 CLDN15 CREB3L1 CYB5R3 ERGIC3 GOLM1 LMNA RNF170 SHISAL1 TEX29 TMEM237 TMEM248
Entrez ID		433	347734
HPRD ID		00152	11576
Ensembl ID		ENSG00000161944	ENSG00000157593
Uniprot IDs		P07307 Q7Z4G9	Q8TB61
PDB IDs
Enriched GO Terms of Interacting Partners?
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