MLLT6 and TNFRSF4

Data Source:
BioGRID (proximity labelling technology)

		MLLT6	TNFRSF4
Description		MLLT6, PHD finger containing	TNF receptor superfamily member 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface
	Molecular Function	Protein Binding Nucleosome Binding Histone Binding Metal Ion Binding	Virus Receptor Activity Tumor Necrosis Factor-activated Receptor Activity Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Positive Regulation Of Sodium Ion Transport Negative Regulation Of Urine Volume Renal Sodium Excretion Renal Potassium Excretion Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Histone H3-K79 Methylation	Positive Regulation Of Immunoglobulin Production Inflammatory Response Immune Response Positive Regulation Of B Cell Proliferation Tumor Necrosis Factor-mediated Signaling Pathway T Cell Proliferation Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Viral Entry Into Host Cell
Pathways			TNFs bind their physiological receptors
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Interacting Genes		25 interacting genes: APP CASK CEBPE CEBPG CEP44 CREB5 CRX ENOX2 GRIPAP1 IKBKG KRTAP10-8 MED15 MEOX2 NSD3 PHC2 PIN1 SPRY2 TCF12 TCF4 TLE5 UBE2G2 UBQLN1 UBQLN4 ZBTB22 ZMYND19	10 interacting genes: NUFIP2 RC3H1 SIVA1 TNFRSF9 TNFSF4 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5
Entrez ID		4302	7293
HPRD ID		08978	02636
Ensembl ID		ENSG00000275023	ENSG00000186827
Uniprot IDs		P55198	P43489
PDB IDs			1D0A 2HEV 2HEY 6OGX 6OKM 6OKN
Enriched GO Terms of Interacting Partners?
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