MLF1 and GMPS

Data Source:
BioGRID (affinity chromatography technology)

		MLF1	GMPS
Description		myeloid leukemia factor 1	guanine monophosphate synthase
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cilium Ciliary Basal Body	Cytosol
	Molecular Function	DNA Binding Protein Binding Protein Domain Specific Binding	GMP Synthase Activity GMP Synthase (glutamine-hydrolyzing) Activity ATP Binding Pyrophosphatase Activity
	Biological Process	Myeloid Progenitor Cell Differentiation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Arrest	GMP Biosynthetic Process Glutamine Metabolic Process Purine Nucleobase Biosynthetic Process Purine Ribonucleoside Monophosphate Biosynthetic Process
Pathways			Purine ribonucleoside monophosphate biosynthesis
Drugs			Glutamic acid
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Depression ( 29700475) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Major depressive disorder ( 27479909) PR interval ( 32439900) Sporadic neuroblastoma ( 28545128) Systolic blood pressure ( 30224653)	Blood metabolite levels ( 27453504) Cardiorespiratory fitness (800m run time) ( 32572135)
Interacting Genes		9 interacting genes: CENPU COP1 COPS3 DNAJB6 GRIK5 MAGEA11 MEOX2 NRBP1 YWHAZ	2 interacting genes: AGPAT2 SUMO4
Entrez ID		4291	8833
HPRD ID		03239	10927
Ensembl ID		ENSG00000178053	ENSG00000163655
Uniprot IDs		A0A0S2Z4U8 A0A140VKD2 B2RD48 P58340 Q2TLE4 Q5HYH4	A0A140VJK6 P49915
PDB IDs		3UAL 3UBW	2VPI 2VXO
Enriched GO Terms of Interacting Partners?
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