ADAM11 and STC2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ADAM11	STC2
Description		ADAM metallopeptidase domain 11	stanniocalcin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Collagen-containing Extracellular Matrix	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Perinuclear Region Of Cytoplasm
	Molecular Function	Metalloendopeptidase Activity Integrin Binding Metallopeptidase Activity	Hormone Activity Enzyme Binding Heme Binding Protein Homodimerization Activity
	Biological Process	Proteolysis Integrin-mediated Signaling Pathway	Cellular Calcium Ion Homeostasis Signal Transduction Embryo Implantation Negative Regulation Of Gene Expression Response To Vitamin D Response To Peptide Hormone Post-translational Protein Modification Cellular Protein Metabolic Process Decidualization Regulation Of Hormone Biosynthetic Process Cellular Response To Hypoxia
Pathways		LGI-ADAM interactions	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)	Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Appendicular lean mass ( 33097823) Atrial fibrillation ( 29892015) Birth weight ( 31043758) Height ( 25429064 31562340) Immunoglobulin A vasculitis ( 28698626) Prostate cancer ( 23535732) Urate levels in overweight individuals ( 25811787)
Interacting Genes		1 interacting genes: STC2	11 interacting genes: ADAM11 AIFM1 ARHGEF40 ARRB2 CARHSP1 EIF2B3 PEBP1 POLR2C POLR3F PPP1R8 PTN
Entrez ID		4185	8614
HPRD ID		01114	04717
Ensembl ID		ENSG00000073670	ENSG00000113739
Uniprot IDs		B4DKD2 O75078	O76061 Q6FHC9
PDB IDs
Enriched GO Terms of Interacting Partners?
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