MBNL1 and ITSN2

Data Source:
BioGRID (two hybrid)

		MBNL1	ITSN2
Description		muscleblind like splicing regulator 1	intersectin 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule	Cytoplasm Centrosome Plasma Membrane Clathrin-coated Pit Presynaptic Membrane Extracellular Exosome Intracellular Vesicle Presynapse
	Molecular Function	RNA Binding Double-stranded RNA Binding Protein Binding Metal Ion Binding	Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding Molecular Adaptor Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Processing Nervous System Development RNA Splicing Embryonic Limb Morphogenesis Regulation Of RNA Splicing Myoblast Differentiation	Endocytosis Viral Process Endosomal Transport Cell Differentiation Regulation Of Catalytic Activity Clathrin-dependent Synaptic Vesicle Endocytosis Positive Regulation Of Dendrite Extension
Pathways			Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Blond vs. brown/black hair color ( 30531825) End-stage renal disease ( 29885931) HDL cholesterol ( 30275531) Heel bone mineral density ( 30598549) Infantile hypertrophic pyloric stenosis ( 22306654) Male-pattern baldness ( 27182965) Prostate cancer ( 29892016) Type 2 diabetes ( 30054458 30297969 32499647) White blood cell count ( 32888494)	Asthma ( 29273806) Chromium levels ( 26025379) Diffuse large B cell lymphoma ( 25261932) Feeling fed-up ( 29500382) Low density lipoprotein cholesterol levels ( 32154731) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309) SjÃ¶gren's syndrome ( 24097067)
Interacting Genes		10 interacting genes: ABI3BP AEN APP BIN1 DAB1 FBXO7 IDH3A ITSN2 TLE5 ZNHIT3	75 interacting genes: AGT AHDC1 AMPH ANKRD17 BCCIP CBL CCDC88C CHIC2 CPSF6 DLGAP1 DST EGFR EPS15L1 EPS8 ERC1 FASLG FCHSD1 FCHSD2 FNBP4 GAREM2 GOLGA2 GOLGA8A GOLGB1 GPNMB HNRNPK HOOK2 ITPKA ITSN1 KCTD10 KDM1A KHDRBS1 KIAA1549 KXD1 LARP6 LSM8 LTBP4 LUC7L3 MAP4K3 MBNL1 MEGF10 NBR1 NR2C2 PDCD6IP PDE4DIP PIK3AP1 PIK3C2B PSEN1 PTN RAD9A RBMX REPS1 RNF20 ROCK1 RUFY1 SEMA6A SH3GL1 SH3KBP1 SNAP29 SOS1 SOS2 STX4 SYN1 SYNJ2 TACC1 TBL3 TMF1 TRIO UBC WAS WASF2 WASL WIPF1 WIPF2 YLPM1 YTHDF1
Entrez ID		4154	50618
HPRD ID		07355	09193
Ensembl ID		ENSG00000152601	ENSG00000198399
Uniprot IDs		Q86VM6 Q9NR56	A6H8W8 Q9NZM3
PDB IDs		3D2N 3D2Q 3D2S 5U6H 5U6L 5U9B	1J3T 1UDL 1UE9 1UFF 1UHF 3GF9 3JZY 4IIO
Enriched GO Terms of Interacting Partners?
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