MAP1A and CACNB4

Data Source:
HPRD (two hybrid)

		MAP1A	CACNB4
Description		microtubule associated protein 1A	calcium voltage-gated channel auxiliary subunit beta 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Microtubule Microtubule Associated Complex Axon Dendrite Neuron Projection Neuronal Cell Body Axon Initial Segment Dendritic Shaft Dendritic Branch Synapse Primary Dendrite Dendritic Microtubule Axon Cytoplasm	Cytosol Plasma Membrane Voltage-gated Calcium Channel Complex Cytoplasmic Side Of Plasma Membrane Synapse
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding Microtubule Binding Cytoskeletal Anchor Activity Tubulin Binding Tau Protein Binding	Voltage-gated Calcium Channel Activity Protein Binding High Voltage-gated Calcium Channel Activity
	Biological Process	Microtubule Cytoskeleton Organization Axonogenesis Memory Associative Learning Dendrite Development Regulation Of Microtubule Depolymerization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Synaptic Plasticity Voluntary Musculoskeletal Movement Neuron Cellular Homeostasis Anterograde Axonal Protein Transport Retrograde Axonal Protein Transport Negative Regulation Of Protein Localization To Microtubule Positive Regulation Of Cellular Protein Localization Neuron Projection Maintenance Positive Regulation Of Protein Localization To Cell Surface	Chemical Synaptic Transmission Neuromuscular Junction Development Membrane Depolarization Cardiac Conduction Calcium Ion Transmembrane Transport Regulation Of Voltage-gated Calcium Channel Activity
Pathways			Presynaptic depolarization and calcium channel opening NCAM1 interactions
Drugs		Estramustine	Ergocalciferol Enflurane Ranolazine Phenytoin Topiramate Nimodipine Spironolactone Magnesium sulfate Levomenthol Miconazole Amiodarone Mibefradil Dronedarone Trimebutine Benidipine Cilnidipine Lacidipine Manidipine Butamben Bioallethrin Bioallethrin Fish oil
Diseases			Episodic ataxias Idiopathic generalied epilepsies (IGEs), including: Childhood absence epilepsy (CAE); Juvenile absence epilepsy (JAE); Juvenile myoclonic epilepsy (JME); Epilepsy with generalized tonic-clonic seizures alone
GWAS		Hemoglobin levels ( 32327693) Platelet count ( 27863252) Plateletcrit ( 27863252) Triglycerides ( 24507774 30275531)	Adverse response to chemotherapy in breast cancer (alopecia) ( 24025145) Idiopathic dilated cardiomyopathy ( 29495422) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
Interacting Genes		23 interacting genes: ACTA1 ACTG1 AP1G1 ARHGEF11 CACNB4 DISC1 DLG1 DLG2 DLG4 GRB2 HTR2A KCNMA1 MAP1B MAP1LC3A NXF1 NXF2 RAPGEF3 RAPGEF4 RHOB SPP1 TUBA4A TUBB UPF2	12 interacting genes: CACNA1A CBX3 CCDC102B CTBP2 EFHC2 FASLG MAP1A MED31 PTN REM1 SYT1 TBL3
Entrez ID		4130	785
HPRD ID		02549	09057
Ensembl ID		ENSG00000166963	ENSG00000182389
Uniprot IDs		P78559 Q504X9	A0A1B0GTK1 A0A1B0GTP5 A0A1B0GTX8 H0Y476 O00305
PDB IDs			2D46
Enriched GO Terms of Interacting Partners?
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