MAGEA4 and UQCRB

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid)
HPRD (two hybrid)

		MAGEA4	UQCRB
Description		MAGE family member A4	ubiquinol-cytochrome c reductase binding protein
Image
GO Annotations	Cellular Component	Cellular_component	Mitochondrial Inner Membrane Mitochondrial Respirasome Mitochondrial Respiratory Chain Complex III
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Biological_process	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Aerobic Respiration
Pathways			Respiratory electron transport
Drugs			2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin 5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS			Huntington's disease progression ( 28642124)
Interacting Genes		27 interacting genes: AMOT AMOTL2 APP ARNT2 BEX2 COX8A GTF3C1 HDDC3 HLA-A LDLRAP1 PICK1 POT1 PSMD10 PUDP RAD18 TEKT4 TIGD5 TK1 TRIM69 TSPYL1 TSPYL4 TXN2 UBXN6 UQCRB UVSSA WBP2 ZNF576	9 interacting genes: ACAP1 ACCS HPCA HSPB1 LRRK2 MAGEA1 MAGEA4 MAGEB4 ZSWIM7
Entrez ID		4103	7381
HPRD ID		02167	11770
Ensembl ID		ENSG00000147381	ENSG00000156467
Uniprot IDs		A0A024RC12 P43358	P14927
PDB IDs		1I4F 2WA0 6TRN 6TRO	5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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