MAFG and NFE2

Data Source:
HPRD (in vivo, in vitro)

		MAFG	NFE2
Description		MAF bZIP transcription factor G	nuclear factor, erythroid 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Chromatin Nucleus Nucleoplasm Cytoplasm PML Body Protein-DNA Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Protein Heterodimerization Activity Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Protein N-terminus Binding WW Domain Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	In Utero Embryonic Development Regulation Of Transcription By RNA Polymerase II Blood Coagulation Adult Behavior Regulation Of Cellular PH Regulation Of Cell Population Proliferation Regulation Of Epidermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Nucleosome Disassembly Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Blood Coagulation Hemostasis Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription, DNA-templated
Pathways		Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production	RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Chronotype ( 30696823) High light scatter reticulocyte count ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean platelet volume ( 22139419 24026423) Mean spheric corpuscular volume ( 32888494) Meat-related diet ( 32066663) Platelet count ( 29403010 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 27863252) Red cell distribution width ( 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		26 interacting genes: ATF3 BACH2 BATF3 CHD3 CREBBP CYP2E1 DDIT3 GTF2A1L HIF1A HOMEZ HOXD12 MAF MAFF MAPK3 MED31 NFE2 NFE2L1 NFE2L2 NFIL3 PAX6 PIDD1 PPP1CA PRRX1 RBM48 SNRPN VIM	21 interacting genes: ATF4 BTRC CREBBP ELF5 HMGN1 ITCH KAT2B MAFF MAFG MAFK MAPK8 NEDD4 NFE2L2 NFE2L3 PEX14 PHYHIP SCAND1 SSX5 TXN WWP1 YAP1
Entrez ID		4097	4778
HPRD ID		03605	09030
Ensembl ID		ENSG00000197063	ENSG00000123405
Uniprot IDs		A0A024R8X1 O15525	A8K3E0 Q16621
PDB IDs			1LVX 2KZ5
Enriched GO Terms of Interacting Partners?
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